退行性二尖瓣修复结果的性别差异。

IF 1.1 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS
Kemin Liu, Qing Ye, Yichen Zhao, Cheng Zhao, Li Song, Jiangang Wang
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引用次数: 0

摘要

目的:本研究探讨退行性二尖瓣修复(MVr)结果的性别差异。方法:对2010 - 2019年北京安贞医院因退行性二尖瓣病变行MVr的1069例患者进行分析。患者平均随访5.1年(四分位数范围:5-7年)。主要终点是总生存期。次要终点是没有再手术和二尖瓣返流复发。倾向匹配分析用于比较男性和女性的结果。结果:女性年龄较大,房颤和中度至重度三尖瓣反流的患病率较高,左心房、左心室舒张末期和左心室收缩末期直径较小。男性更有可能同时进行冠状动脉旁路移植术,并且体外循环和主动脉交叉夹夹的时间更长。结论:女性手术时间较晚,并发症发生率高于男性。长期生存率和不再手术率在两性间无显著差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Sex Differences in the Outcomes of Degenerative Mitral Valve Repair.

Sex Differences in the Outcomes of Degenerative Mitral Valve Repair.

Sex Differences in the Outcomes of Degenerative Mitral Valve Repair.

Sex Differences in the Outcomes of Degenerative Mitral Valve Repair.

Purpose: This study explored the sex differences in the outcomes of degenerative mitral valve repair (MVr).

Methods: From 2010 to 2019, 1069 patients who underwent MVr due to degenerative mitral disease at Beijing Anzhen Hospital were analyzed. The average patient follow-up was 5.1 years (interquartile range: 5-7 years). The primary endpoint was overall survival. Secondary endpoints were freedom from reoperation and recurrent mitral regurgitation. A propensity-matched analysis was used to compare the outcomes of males and females.

Results: Females were older, had a higher prevalence of atrial fibrillation and moderate-to-severe tricuspid regurgitation, and had smaller left atrial, left ventricular end-diastolic, and left ventricular end-systolic diameters. Males were more likely to undergo concomitant coronary artery bypass grafting and had longer cardiopulmonary bypass and aortic cross-clamp times. The in-hospital mortality was <1% (10/1,069). After propensity score matching of 331 pairs of patients, most variables were well balanced. Before and after propensity score matching, the long-term survival and freedom from reoperation rates were similar. Males had higher durability after surgery compared with females.

Conclusions: Females were referred to surgery later and had more complications than males. Long-term survival and freedom from reoperation rates were not significantly different between the sexes.

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来源期刊
Annals of Thoracic and Cardiovascular Surgery
Annals of Thoracic and Cardiovascular Surgery CARDIAC & CARDIOVASCULAR SYSTEMS-SURGERY
CiteScore
2.80
自引率
0.00%
发文量
56
审稿时长
4-8 weeks
期刊介绍: Information not localized
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