COVID-19住院患者出院后的慢性疼痛：一项观察性研究。

IF 1.7 4区医学 Q2 ANESTHESIOLOGY

Brazilian Journal of Anesthesiology Pub Date : 2024-07-01 DOI:10.1016/j.bjane.2023.08.001

Guilherme Antonio Moreira de Barros, Douglas Inomata Cardoso da Silva, Mariana Lopes Amaral Barbosa, Rafael Abbud Soares, Rodrigo Leal Alves, Claudio Lucas Miranda, Paula Danieli Lopes da Costa, Paulo do Nascimento Júnior, Norma Sueli Pinheiro Módolo

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引用次数: 0

摘要

背景：有关冠状病毒病2019（COVID-19）出院后疼痛症状的发生率和性质的研究很少，尤其是发生中重度疾病的患者。因此，本研究旨在评估因COVID-19住院后出院的患者是否存在慢性疼痛，以及慢性疼痛的存在与重症监护住院时间、人口统计学和最坏的严重急性呼吸系统综合征冠状病毒2（SARS-CoV-2）结果的风险因素之间的关系：对住院后康复的 COVID-19 患者进行了横断面观察研究。研究人员在患者出院至少 3 个月后对其进行招募，并查阅了他们在医院的健康档案。评估的变量包括人口统计学、SARS-CoV-2 感染的严重程度（考虑是否需要重症监护）以及是否存在慢性疼痛。研究结果以描述性方式显示，多变量分析以研究结果的比值比（ORs）和各自的置信区间（CIs）表示。统计显著性以 p < 0.05 为标准：在纳入的 242 人中，77 人（31.8%）报告了与 COVID-19 相关的慢性疼痛，但与感染的严重程度无关。女性和肥胖与较高的慢性疼痛风险有关，其OR值分别为2.69（置信区间[95% CI 1.4至5.0]）和3.02（95% CI 1.5至5.9）。四肢是受影响最严重的部位：结论：在医院环境中接受治疗的 COVID-19 幸存者中，慢性疼痛很常见。结论：慢性疼痛在医院环境中接受治疗的 COVID-19 存活者中很常见，女性和肥胖是导致慢性疼痛发生的风险因素。

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Chronic pain after hospital discharge on patients hospitalized for COVID-19: an observational study

Background

There are few studies related to Coronavirus Disease 2019 (COVID-19) on the prevalence and nature of pain symptoms after hospital discharge, especially in individuals who develop moderate to severe disease forms. Therefore, this study aimed to evaluate the presence of chronic pain in patients discharged after hospitalization for COVID-19, and the relationship between the presence of chronic pain and intensive care stay, demographics, and risk factors for the worst Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) outcome.

Methods

A cross-sectional observational study was carried out on patients with COVID-19 who recovered after hospitalization. Patients were recruited at the least 3 months after discharge and their hospital's health files were prospected. The variables evaluated were demographics, the severity of SARS-CoV-2 infection (considering the need for intensive care), and the presence of chronic pain. The results were shown in a descriptive manner, and multivariate analysis expressed as Odds Ratios (ORs) and respective Confidence Intervals (CIs) for the outcomes studied. Statistical significance was set at p < 0.05.

Results

Of 242 individuals included, 77 (31.8%) reported chronic pain related to COVID-19, with no correlation with the severity of infection. Female sex and obesity were associated with a higher risk for chronic pain with ORs of 2.69 (Confidence Interval [95% CI 1.4 to 5.0]) and 3.02 (95% CI 1.5 to 5.9). The limbs were the most affected areas of the body.