男性不育。

IF 76.9 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Michael L Eisenberg, Sandro C Esteves, Dolores J Lamb, James M Hotaling, Aleksander Giwercman, Kathleen Hwang, Yu-Sheng Cheng
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引用次数: 0

摘要

临床不孕是指一对夫妇在尝试了12个月后无法怀孕。据估计,男性因素导致30-50%的不孕病例。不孕或生育能力下降可能由睾丸功能障碍、内分泌疾病、生活方式因素(如烟草和肥胖)、先天解剖因素、性腺毒性暴露和衰老等引起。男性不育的评估包括详细的病史记录、重点体检和选择性实验室检测,包括精液分析。治疗包括生活方式优化、经验或靶向药物治疗以及可显著提高生育率的手术治疗。尽管男性不育被认为是一种影响不育夫妇双方生活质量的疾病,但与其他健康相关疾病相比,关于具体量化和影响的数据较少。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Male infertility.

Male infertility.

Clinical infertility is the inability of a couple to conceive after 12 months of trying. Male factors are estimated to contribute to 30-50% of cases of infertility. Infertility or reduced fertility can result from testicular dysfunction, endocrinopathies, lifestyle factors (such as tobacco and obesity), congenital anatomical factors, gonadotoxic exposures and ageing, among others. The evaluation of male infertility includes detailed history taking, focused physical examination and selective laboratory testing, including semen analysis. Treatments include lifestyle optimization, empirical or targeted medical therapy as well as surgical therapies that lead to measurable improvement in fertility. Although male infertility is recognized as a disease with effects on quality of life for both members of the infertile couple, fewer data exist on specific quantification and impact compared with other health-related conditions.

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来源期刊
Nature Reviews Disease Primers
Nature Reviews Disease Primers Medicine-General Medicine
CiteScore
76.70
自引率
0.20%
发文量
75
期刊介绍: Nature Reviews Disease Primers, a part of the Nature Reviews journal portfolio, features sections on epidemiology, mechanisms, diagnosis, management, and patient quality of life. The editorial team commissions top researchers — comprising basic scientists and clinical researchers — to write the Primers, which are designed for use by early career researchers, medical students and principal investigators. Each Primer concludes with an Outlook section, highlighting future research directions. Covered medical specialties include Cardiology, Dermatology, Ear, Nose and Throat, Emergency Medicine, Endocrinology, Gastroenterology, Genetic Conditions, Gynaecology and Obstetrics, Hepatology, Haematology, Infectious Diseases, Maxillofacial and Oral Medicine, Nephrology, Neurology, Nutrition, Oncology, Ophthalmology, Orthopaedics, Psychiatry, Respiratory Medicine, Rheumatology, Sleep Medicine, and Urology.
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