危重症患者静脉与动脉血对血栓微观结构影响的比较研究。止血生物标志物的诊断潜力评估。

IF 2.1 Q3 CRITICAL CARE MEDICINE

Journal of the Intensive Care Society Pub Date : 2023-05-01 DOI:10.1177/17511437211060154

Suresh Pillai, Vanessa Evans, Gareth Davies, Matthew J Lawrence, Janet Whitley, Ceri E Battle, Phylip R Williams, Keith Morris, Phillip A Evans

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引用次数: 0

摘要

用于凝血分析的血液可以从重症监护病房(ICU)的动脉或静脉系统取样。通过分形分析(df)测定血块的微观结构和强度，为血管止血疾病和脓毒症提供了有价值的信息。我们的目的是确定是否可以在动脉血或静脉血中平等和比较地测量df，并招募了45名ICU危重患者。研究发现，在动脉血中可以很容易地测量Df，其结果与静脉血中的结果相当，这增加了Df作为这些患者止血的潜在标记物的价值。

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A comparative study into the effects of venous and arterial blood on clot microstructure in critically unwell patients. Assessment of the diagnostic potential of a biomarker of haemostasis.

Blood for coagulation analysis can be sampled from the arterial or venous system in intensive care units (ICU). The determination of clot microstructure and strength by fractal analysis (d_f) gives valuable information in a range of vascular haemostatic disease and sepsis. We aimed to determine if d_f could be measured equally and comparatively in arterial or venous blood, and 45 critically ill patients in an ICU were recruited. d_f was found to be readily measured in arterial blood with results comparable to those in venous blood and that add value of d_f as a potential marker of haemostasis in these patients.

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来源期刊

Journal of the Intensive Care Society Nursing-Critical Care Nursing

CiteScore

4.40

自引率

0.00%

发文量

期刊介绍： The Journal of the Intensive Care Society (JICS) is an international, peer-reviewed journal that strives to disseminate clinically and scientifically relevant peer-reviewed research, evaluation, experience and opinion to all staff working in the field of intensive care medicine. Our aim is to inform clinicians on the provision of best practice and provide direction for innovative scientific research in what is one of the broadest and most multi-disciplinary healthcare specialties. While original articles and systematic reviews lie at the heart of the Journal, we also value and recognise the need for opinion articles, case reports and correspondence to guide clinically and scientifically important areas in which conclusive evidence is lacking. The style of the Journal is based on its founding mission statement to ‘instruct, inform and entertain by encompassing the best aspects of both tabloid and broadsheet''.