NK/T和外周T细胞淋巴瘤的循环肿瘤DNA。

IF 5 3区医学 Q1 HEMATOLOGY

Seminars in hematology Pub Date : 2023-07-01 DOI:10.1053/j.seminhematol.2023.07.003

Yu-Jia Huo , Wei-Li Zhao

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引用次数: 0

摘要

自然杀伤（NK）/T细胞淋巴瘤（NK/TCL）和外周T细胞淋巴瘤（PTCL）是侵袭性血液系统恶性肿瘤。随着下一代测序技术的发展，循环肿瘤DNA（ctDNA）可以通过几种具有临床意义的技术进行检测。到目前为止，ctDNA在NK/TCL和PTCL治疗前预后预测、治疗反应纵向监测和长期缓解或复发监测中的作用已在多项研究中报道。

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Circulating tumor DNA in NK/T and peripheral T cell lymphoma

Natural killer (NK)/T-cell lymphomas (NK/TCL) and peripheral T-cell lymphomas (PTCL) are aggressive hematological malignancies. With the development of next-generation sequencing, circulating tumor DNA (ctDNA) can be detected by several techniques with clinical implications. So far, the effect of ctDNA in pretreatment prognosis prediction, longitudinal monitoring of treatment response and surveillance of long-term remission or relapse in NK/TCL and PTCL has been reported in several researches.

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来源期刊

Seminars in hematology 医学-血液学

CiteScore

6.20

自引率

2.80%

发文量

审稿时长

35 days

期刊介绍： Seminars in Hematology aims to present subjects of current importance in clinical hematology, including related areas of oncology, hematopathology, and blood banking. The journal''s unique issue structure allows for a multi-faceted overview of a single topic via a curated selection of review articles, while also offering a variety of articles that present dynamic and front-line material immediately influencing the field. Seminars in Hematology is devoted to making the important and current work accessible, comprehensible, and valuable to the practicing physician, young investigator, clinical practitioners, and internists/paediatricians with strong interests in blood diseases. Seminars in Hematology publishes original research, reviews, short communications and mini- reviews.