评估零母亲死亡率子痫前期项目对西爪哇万隆单一中心孕产妇死亡率的影响(2015-2022):一项回顾性研究

Adhi Pribadi, Dini Hidayat, R M Sonny Sasotya, Muhammad Alamsyah Aziz, Windi Nurdiawan, Akhmad Yogi Pramatirta, Amillia Siddiq, Johanes Cornelius Mose, Yudi Mulyana Hidayat, Annisa Dewi Nugrahani, Dhanny Primantara Johari Santoso, Wiryawan Permadi
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引用次数: 0

摘要

零母亲死亡率子痫前期(ZOOM)项目是一项加速倡议,旨在抑制与妊娠期高血压疾病相关的死亡率,包括子痫前期。这项在西爪哇万隆进行的单中心回顾性研究旨在评估2015年至2022年实施的ZOOM计划的影响。材料和方法我们分析了19176例分娩和与妊娠期高血压相关的孕产妇死亡。通过血压测量、实验室检测(包括尿蛋白、肝功能、血液谱、血小板、x射线、超声心动图和COVID-19检测)来验证诊断。评估病死率(CFR)以评估ZOOM计划的影响。结果25.1%的妊娠期高血压,其中9.8%和1.4%分别归因于先兆子痫和子痫。与高血压相关的孕产妇死亡占36.6%,其中大多数与子痫有关。最常见的并发症是心力衰竭(45.5%)和溶血、肝酶升高和低血小板(HELLP)综合征(22%)。CFR从2018年的61%下降到2022年的10%。2015年至2022年的总CFR为1.3%,其中子痫病例的死亡率最高(9.4%)。然而,自2018年以来出现下降趋势,2021年达到0.2%的低点。结论ZOOM方案的实施,包括子痫前期再教育、早期发现、及时干预、方案调整和完善转诊制度,使孕产妇高血压妊娠障碍死亡率显著降低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Assessing the Impact of the Zero Mother Mortality Preeclampsia Program on Maternal Mortality Rates at a Single Center in Bandung, West Java (2015-2022): A Retrospective Study.

Assessing the Impact of the Zero Mother Mortality Preeclampsia Program on Maternal Mortality Rates at a Single Center in Bandung, West Java (2015-2022): A Retrospective Study.

BACKGROUND The Zero Mother Mortality Preeclampsia (ZOOM) program was adopted as an accelerated initiative to curb mortality related to hypertensive disorders in pregnancy, including preeclampsia. This single-center, retrospective study in Bandung, West Java, aims to evaluate the impact of the ZOOM program implemented from 2015 to 2022. MATERIAL AND METHODS We analyzed 19,176 childbirths and associated maternal deaths due to hypertension in pregnancy. Diagnoses were validated using blood pressure measures, lab tests including urine protein, liver function, blood profiles, platelets, X-ray, echocardiography, and COVID-19 testing. The case fatality rate (CFR) was assessed to evaluate the impact of the ZOOM program. RESULTS Hypertension in pregnancy was identified in 25.1% of cases, with 9.8% and 1.4% attributed to preeclampsia and eclampsia, respectively. Maternal deaths associated with hypertension accounted for 36.6%, with the majority linked to eclampsia. Heart failure (45.5%) and Hemolysis, Elevated Liver enzymes, and Low Platelets (HELLP) syndrome (22%) were the most common complications. The CFR decreased from 61% in 2018 to 10% in 2022. The overall CFR from 2015 to 2022 was 1.3%, with the highest fatality rate observed in eclampsia cases (9.4%). However, a declining trend was seen since 2018, reaching a low of 0.2% in 2021. CONCLUSIONS The implementation of the ZOOM program, which includes preeclampsia re-education, early detection, prompt intervention, protocol adjustments, and a refined referral system, led to a marked reduction in maternal deaths from hypertensive pregnancy disorders.

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