耳蜗植入术后早期阻抗变化指示的电生理状态:文献综述。

IF 1.9 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL
Lieber Po-Hung Li
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引用次数: 0

摘要

人工耳蜗植入是重度到重度听力损失的主要治疗选择。人工耳蜗植入术通过插入耳蜗,刺激耳蜗神经,可以改善植入者的听力和语言表现。耳蜗的微环境是先天的,当异物进入时就会受到干扰。然而,在分子水平上,耳蜗内电生理的实时变化永远无法在人体内进行研究。因此,阻抗是反映耳蜗内电生理的良好指标。由于阻抗的初始测量不能早于传统的术后1个月的间隔时间,因此直到最近才探索阻抗的早期变化;然而,外科医生现在正在尝试在植入后不到1个月的时间内启动初始开关。本文综述了早期接通后的电生理变化情况
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Electrophysiological status indexed by early changes in impedance after cochlear implantation: A literature review.

Cochlear implantation is a major treatment option for severe-to-profound hearing loss. By insertion into the cochlea and stimulation of the cochlear nerve, cochlear implantation can improve the performance of hearing and speech performance of the implantees. The microenvironment of the cochlea is innate and gets disturbed in response to the insertion of a foreign body. However, real-time changes inside the cochlea in terms of electrophysiology at the molecular level can never be investigated in vivo in human beings. Thus, impedance is a good guide that reflects the electrophysiology inside the cochlea. Because the initial measurement of impedance cannot be performed earlier than the traditional interval of 1 month postoperatively, early changes in impedance have not been explored until recently; however, surgeons are now trying the initial switch-on earlier than 1 month after implantation. This review discusses the scenario of electrophysiological variation after early switch-on in <1 day postimplantation. Evidence has shown that fluctuations in impedance after implantation depend on the interplay between cell cover formation, fibrosis, electrode design, and electrical stimulation. Further studies addressing the correlation between impedance and clinical parameters are required to develop reliable biomarkers for better performance of cochlear implantation.

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来源期刊
Journal of the Chinese Medical Association
Journal of the Chinese Medical Association MEDICINE, GENERAL & INTERNAL-
CiteScore
6.20
自引率
13.30%
发文量
320
审稿时长
15.5 weeks
期刊介绍: Journal of the Chinese Medical Association, previously known as the Chinese Medical Journal (Taipei), has a long history of publishing scientific papers and has continuously made substantial contribution in the understanding and progress of a broad range of biomedical sciences. It is published monthly by Wolters Kluwer Health and indexed in Science Citation Index Expanded (SCIE), MEDLINE®, Index Medicus, EMBASE, CAB Abstracts, Sociedad Iberoamericana de Informacion Cientifica (SIIC) Data Bases, ScienceDirect, Scopus and Global Health. JCMA is the official and open access journal of the Chinese Medical Association, Taipei, Taiwan, Republic of China and is an international forum for scholarly reports in medicine, surgery, dentistry and basic research in biomedical science. As a vehicle of communication and education among physicians and scientists, the journal is open to the use of diverse methodological approaches. Reports of professional practice will need to demonstrate academic robustness and scientific rigor. Outstanding scholars are invited to give their update reviews on the perspectives of the evidence-based science in the related research field. Article types accepted include review articles, original articles, case reports, brief communications and letters to the editor
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