基于高选择性和高灵敏度电化学适体的传感器的最新进展。

IF 3.1 4区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemical Research in Chinese Universities Pub Date : 2022-01-01 Epub Date: 2022-05-05 DOI:10.1007/s40242-022-2084-z

Tianwei Tang, Yinghuan Liu, Ying Jiang

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引用次数: 0

摘要

高选择性、灵敏和稳定的生物传感器对于在分子水平上理解许多生理活动和疾病至关重要。基于电化学适体的（E-AB）传感器是生物系统中一个很有吸引力的测量平台，这归因于适体的高选择性和电化学分析的高灵敏度的综合优势。本文综述了E-AB传感器的最新发展，重点介绍了传感器制造中使用的修饰策略和生物系统中不同大小分析物的传感策略，并展望了基于电化学适体的传感器未来发展的挑战和前景。

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Recent Progress on Highly Selective and Sensitive Electrochemical Aptamer-based Sensors.

Highly selective, sensitive, and stable biosensors are essential for the molecular level understanding of many physiological activities and diseases. Electrochemical aptamer-based (E-AB) sensor is an appealing platform for measurement in biological system, attributing to the combined advantages of high selectivity of the aptamer and high sensitivity of electrochemical analysis. This review summarizes the latest development of E-AB sensors, focuses on the modification strategies used in the fabrication of sensors and the sensing strategies for analytes of different sizes in biological system, and then looks forward to the challenges and prospects of the future development of electrochemical aptamer-based sensors.

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来源期刊

Chemical Research in Chinese Universities 化学-化学综合

CiteScore

5.30

自引率

6.50%

发文量

152

审稿时长

3.0 months

期刊介绍： The journal publishes research articles, letters/communications and reviews written by faculty members, researchers and postgraduates in universities, colleges and research institutes all over China and overseas. It reports the latest and most creative results of important fundamental research in all aspects of chemistry and of developments with significant consequences across subdisciplines. Main research areas include (but are not limited to): Organic chemistry (synthesis, characterization, and application); Inorganic chemistry (bio-inorganic chemistry, inorganic material chemistry); Analytical chemistry (especially chemometrics and the application of instrumental analysis and spectroscopy); Physical chemistry (mechanisms, catalysis, thermodynamics and dynamics); Polymer chemistry and polymer physics (mechanisms, material, catalysis, thermodynamics and dynamics); Quantum chemistry (quantum mechanical theory, quantum partition function, quantum statistical mechanics); Biochemistry; Biochemical engineering; Medicinal chemistry; Nanoscience (nanochemistry, nanomaterials).