抗胆碱能作用很少是好事。

IF 3.4 3区医学 Q2 PHARMACOLOGY & PHARMACY

Therapeutic Advances in Psychopharmacology Pub Date : 2023-01-01 DOI:10.1177/20451253231195264

Delia Bishara

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引用次数: 0

摘要

在过去的二十年中，与抗胆碱能药物相关的风险证据显著增加。它们不仅会引起口干、视力模糊和便秘等外围副作用，还会引起认知障碍等中枢效应;最近，它们一直与老年人患痴呆症和死亡的风险增加有关。本文综述了抗胆碱能药物与痴呆风险和痴呆死亡率增加相关的证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Anticholinergic action is rarely a good thing.

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Anticholinergic action is rarely a good thing.

The evidence for the risks associated with anticholinergic agents has grown considerably in the last two decades. Not only are they associated with causing peripheral side effects such as dry mouth, blurred vision and constipation, but they can also cause central effects such as cognitive impairment; and more recently, they have consistently been linked with an increased risk of dementia and death in older people. This paper reviews the evidence for the associations of anticholinergic agents and the risk of dementia and increased mortality in dementia.

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来源期刊

Therapeutic Advances in Psychopharmacology Multiple-

CiteScore

7.90

自引率

2.40%

发文量

审稿时长

10 weeks

期刊介绍： Therapeutic Advances in Psychopharmacology delivers the highest quality peer-reviewed articles, reviews, and scholarly comment on pioneering efforts and innovative studies across all areas of psychopharmacology. The journal has a strong clinical and pharmacological focus and is aimed at clinicians and researchers in psychopharmacology, providing a forum in print and online for publishing the highest quality articles in this area.