简而言之:Melphalan (Hepzato)治疗葡萄膜黑色素瘤。

IF 1.4 4区医学 Q4 PHARMACOLOGY & PHARMACY

Medical Letter on Drugs and Therapeutics Pub Date : 2023-09-04 DOI:10.58347/tml.2023.1684d

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In brief: Melphalan (Hepzato) for uveal melanoma.

The alkylating agent melphalan (Hepzato – Delcath) has been approved by the FDA for treatment of uveal melanoma in adults with unresectable hepatic metastases that affects <50% of the liver and no extrahepatic disease, or extrahepatic disease limited to the bone, lymph nodes, subcutaneous tissues, or lung that is amenable to resection or radiation.

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来源期刊

Medical Letter on Drugs and Therapeutics 医学-药学

CiteScore

1.00

自引率

42.10%

发文量

审稿时长

6-12 weeks

期刊介绍： The Medical Letter, Inc. is committed to providing objective, practical, and timely information on drugs and treatments of common diseases to help our readers make the best decisions for their patients—without the influence of the pharmaceutical industry. The Medical Letter On Drugs and Therapeutics is a biweekly publication that provides: Evidence-based, peer-reviewed evaluations of new FDA-approved drugs with conclusions reached by a consensus of experts New information on previously approved drugs including pivotal clinical trials, new indications, and safety warnings Consensus recommendations for the preferred and alternative treatments for common disorders Comparative reviews of drugs for a given indication with particular attention to clinical efficacy, adverse effects, drug interactions, and cost.