{"title":"LED光生物调节对牙种植体骨整合影响的体内研究。","authors":"Jean-Marc Foletti, Floriane Remy, Luc Chevenement, Manon Sterba, Patrick Tavitian, Laurent Badih, Olivia Kenck-Veran","doi":"10.34172/joddd.2023.36954","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Photobiomodulation (PBM) may be prescribed after dental surgery to accelerate tissue healing and improve implant stability. The objective of this study is to evaluate the efficiency of LED-PBM on the dental implant osseointegration.</p><p><strong>Methods: </strong>A total of 48 implants (Kontact<sup>TM</sup>) were inserted in 8 Yucatan minipigs (6 implants per minipig) divided into 2 groups (test and control). The test group received LED-PBM with a total energy of 124.2 J/cm<sup>2</sup> delivered over 4 sessions (at day0, day+8, day+15 and day+28) lasting 12 minutes each. At day+28, all animals were sacrificed, and their mandibles removed to perform histologic and histomorphometric analysis. Implant osseointegration was evaluated using the computation of bone/implant contact (BIC) index and bone surface/total surface (BS/ TS) ratio. The groups were compared using Student's unpaired <i>t</i> test.</p><p><strong>Results: </strong>BIC index and BS/TS ratio were significantly higher within the test group as compared to the control group (<i>P</i><0.01). Histologic observations on bone tissues demonstrated that LED-PBM may improve and accelerate dental implant osseointegration: 25% of dental implants analyzed within the test group were completely osseointegrated, versus 12.5% within the control group.</p><p><strong>Conclusion: </strong>This experimental study indicates that LED-PBM contributes to enhancing implant treatment outcomes.</p>","PeriodicalId":15599,"journal":{"name":"Journal of Dental Research, Dental Clinics, Dental Prospects","volume":"17 1","pages":"28-34"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462914/pdf/","citationCount":"0","resultStr":"{\"title\":\"Effect of LED photobiomodulation on dental implant osseointegration: An in vivo study.\",\"authors\":\"Jean-Marc Foletti, Floriane Remy, Luc Chevenement, Manon Sterba, Patrick Tavitian, Laurent Badih, Olivia Kenck-Veran\",\"doi\":\"10.34172/joddd.2023.36954\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Photobiomodulation (PBM) may be prescribed after dental surgery to accelerate tissue healing and improve implant stability. The objective of this study is to evaluate the efficiency of LED-PBM on the dental implant osseointegration.</p><p><strong>Methods: </strong>A total of 48 implants (Kontact<sup>TM</sup>) were inserted in 8 Yucatan minipigs (6 implants per minipig) divided into 2 groups (test and control). The test group received LED-PBM with a total energy of 124.2 J/cm<sup>2</sup> delivered over 4 sessions (at day0, day+8, day+15 and day+28) lasting 12 minutes each. At day+28, all animals were sacrificed, and their mandibles removed to perform histologic and histomorphometric analysis. Implant osseointegration was evaluated using the computation of bone/implant contact (BIC) index and bone surface/total surface (BS/ TS) ratio. The groups were compared using Student's unpaired <i>t</i> test.</p><p><strong>Results: </strong>BIC index and BS/TS ratio were significantly higher within the test group as compared to the control group (<i>P</i><0.01). Histologic observations on bone tissues demonstrated that LED-PBM may improve and accelerate dental implant osseointegration: 25% of dental implants analyzed within the test group were completely osseointegrated, versus 12.5% within the control group.</p><p><strong>Conclusion: </strong>This experimental study indicates that LED-PBM contributes to enhancing implant treatment outcomes.</p>\",\"PeriodicalId\":15599,\"journal\":{\"name\":\"Journal of Dental Research, Dental Clinics, Dental Prospects\",\"volume\":\"17 1\",\"pages\":\"28-34\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462914/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Dental Research, Dental Clinics, Dental Prospects\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.34172/joddd.2023.36954\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Dentistry\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Dental Research, Dental Clinics, Dental Prospects","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.34172/joddd.2023.36954","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Dentistry","Score":null,"Total":0}
Effect of LED photobiomodulation on dental implant osseointegration: An in vivo study.
Background: Photobiomodulation (PBM) may be prescribed after dental surgery to accelerate tissue healing and improve implant stability. The objective of this study is to evaluate the efficiency of LED-PBM on the dental implant osseointegration.
Methods: A total of 48 implants (KontactTM) were inserted in 8 Yucatan minipigs (6 implants per minipig) divided into 2 groups (test and control). The test group received LED-PBM with a total energy of 124.2 J/cm2 delivered over 4 sessions (at day0, day+8, day+15 and day+28) lasting 12 minutes each. At day+28, all animals were sacrificed, and their mandibles removed to perform histologic and histomorphometric analysis. Implant osseointegration was evaluated using the computation of bone/implant contact (BIC) index and bone surface/total surface (BS/ TS) ratio. The groups were compared using Student's unpaired t test.
Results: BIC index and BS/TS ratio were significantly higher within the test group as compared to the control group (P<0.01). Histologic observations on bone tissues demonstrated that LED-PBM may improve and accelerate dental implant osseointegration: 25% of dental implants analyzed within the test group were completely osseointegrated, versus 12.5% within the control group.
Conclusion: This experimental study indicates that LED-PBM contributes to enhancing implant treatment outcomes.
期刊介绍：
Journal of Dental Research Dental Clinics Dental Prospects (JODDD) is a Platinum* Open Access, peer-reviewed quarterly indexed journal that publishes articles of basic, clinical, and prospective nature in all areas of dentistry and oral health.
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