Masahiro Kataoka, Kuniyuki Gomi, Ken Ichioka, Takuya Iguchi, Tomoki Shirota, Arano Makino, Ko Shimada, Kiyotomi Maruyama, Motohiro Mihara, Shoji Kajikawa
{"title":"腹腔镜结直肠癌术后第7天c反应蛋白/白蛋白比值对预后的影响","authors":"Masahiro Kataoka, Kuniyuki Gomi, Ken Ichioka, Takuya Iguchi, Tomoki Shirota, Arano Makino, Ko Shimada, Kiyotomi Maruyama, Motohiro Mihara, Shoji Kajikawa","doi":"10.3393/ac.2022.00234.0033","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>C-reactive protein to albumin ratio (CAR) has been utilized as a prognostic factor in various carcinomas. We investigated the relationship between preoperative, postoperative day (POD) 1, and POD 7 CARs and the prognosis of patients with colorectal cancer (CRC).</p><p><strong>Methods: </strong>Three hundred twenty patients with CRC who underwent laparoscopic radical resection between May 2011 and December 2016 were enrolled. Patients were selected into 2 groups, high CAR and low CAR (n=72/group), based on preoperative, POD 1, and POD 7 CARs. The relapse-free survival (RFS) and overall survival (OS) were compared between groups using propensity score matching.</p><p><strong>Results: </strong>The high CAR group had a significantly worse RFS (P<0.001) and OS (P=0.002) at POD 7 than those in the low CAR group. However, in preoperative and POD 1 analysis, no differences were observed.</p><p><strong>Conclusion: </strong>In patients with CRC, CAR of POD 7 was a significant prognostic factor.</p>","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":"39 4","pages":"315-325"},"PeriodicalIF":3.0000,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/10/c3/ac-2022-00234-0033.PMC10475807.pdf","citationCount":"3","resultStr":"{\"title\":\"Clinical impact of C-reactive protein to albumin ratio of the 7th postoperative day on prognosis after laparoscopic colorectal cancer surgery.\",\"authors\":\"Masahiro Kataoka, Kuniyuki Gomi, Ken Ichioka, Takuya Iguchi, Tomoki Shirota, Arano Makino, Ko Shimada, Kiyotomi Maruyama, Motohiro Mihara, Shoji Kajikawa\",\"doi\":\"10.3393/ac.2022.00234.0033\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>C-reactive protein to albumin ratio (CAR) has been utilized as a prognostic factor in various carcinomas. We investigated the relationship between preoperative, postoperative day (POD) 1, and POD 7 CARs and the prognosis of patients with colorectal cancer (CRC).</p><p><strong>Methods: </strong>Three hundred twenty patients with CRC who underwent laparoscopic radical resection between May 2011 and December 2016 were enrolled. Patients were selected into 2 groups, high CAR and low CAR (n=72/group), based on preoperative, POD 1, and POD 7 CARs. The relapse-free survival (RFS) and overall survival (OS) were compared between groups using propensity score matching.</p><p><strong>Results: </strong>The high CAR group had a significantly worse RFS (P<0.001) and OS (P=0.002) at POD 7 than those in the low CAR group. However, in preoperative and POD 1 analysis, no differences were observed.</p><p><strong>Conclusion: </strong>In patients with CRC, CAR of POD 7 was a significant prognostic factor.</p>\",\"PeriodicalId\":8267,\"journal\":{\"name\":\"Annals of Coloproctology\",\"volume\":\"39 4\",\"pages\":\"315-325\"},\"PeriodicalIF\":3.0000,\"publicationDate\":\"2023-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/10/c3/ac-2022-00234-0033.PMC10475807.pdf\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of Coloproctology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3393/ac.2022.00234.0033\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"GASTROENTEROLOGY & HEPATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Coloproctology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3393/ac.2022.00234.0033","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
Clinical impact of C-reactive protein to albumin ratio of the 7th postoperative day on prognosis after laparoscopic colorectal cancer surgery.
Purpose: C-reactive protein to albumin ratio (CAR) has been utilized as a prognostic factor in various carcinomas. We investigated the relationship between preoperative, postoperative day (POD) 1, and POD 7 CARs and the prognosis of patients with colorectal cancer (CRC).
Methods: Three hundred twenty patients with CRC who underwent laparoscopic radical resection between May 2011 and December 2016 were enrolled. Patients were selected into 2 groups, high CAR and low CAR (n=72/group), based on preoperative, POD 1, and POD 7 CARs. The relapse-free survival (RFS) and overall survival (OS) were compared between groups using propensity score matching.
Results: The high CAR group had a significantly worse RFS (P<0.001) and OS (P=0.002) at POD 7 than those in the low CAR group. However, in preoperative and POD 1 analysis, no differences were observed.
Conclusion: In patients with CRC, CAR of POD 7 was a significant prognostic factor.
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