[活体供体肠移植]。

G S Wu, Z X Liu, L Zhao, T B Liang
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引用次数: 0

摘要

由于外科技术、围手术期护理和新型免疫抑制剂的进步,肠移植已成为治疗慢性肠衰竭的有效选择。肠移植最常见的是使用已故捐赠,而其中只有不到2%来自活体捐赠。活体供体肠移植获得节段性肠移植物,通常来自近亲。初步结果表明,活体供体肠移植后,急性/慢性排斥反应率、术后机会性感染和移植物抗宿主病显著降低,有助于提高移植物和患者的生存率。由于器官捐献严重短缺,尤其是儿童器官捐献,活体肠移植已日益成为中国慢性肠衰竭患者的重要治疗选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Living-donor intestinal transplantation].

Due to advances in surgical techniques, perioperative care, and new immunosuppressive agents, intestinal transplantation has become a valid therapeutic choice for chronic intestinal failure. Intestinal transplantation has been performed most commonly using deceased donation, while less than 2% of which have been from living donation. Living donor intestinal transplantation obtaining a segmental intestinal graft, usually from close relatives. Preliminary results show that acute/chronic rejection rates, postoperative opportunistic infections, and graft versus host disease are significantly reduced after living donor intestinal transplantation, contributing to improved graft and patient survivals. Due to a severe shortage of organ donation, especially in children, living donor intestinal transplantation has increasingly become an important treatment option for patients with chronic intestinal failure in China.

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