加拿大安大略省健康母马细小病毒肝炎患病率

IF 1.1 4区 农林科学 Q2 Veterinary
Maria A Papapetrou, Luis G Arroyo, Toni L Meister, John D Baird, Eike Steinmann, Brandon N Lillie
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引用次数: 0

摘要

马细小病毒肝炎(EqPV-H)于2018年在美国首次从一匹被诊断患有泰勒氏病的马的血清和肝脏组织中报道。泰勒氏病,又称马血清肝炎,是一种伴有暴发性肝坏死的严重肝炎。该疾病最常在服用马源性生物制品后报告;然而,也有报道说,在没有事先给药的接触马中。EqPV-H已在北美(美国、加拿大)、欧洲(德国、奥地利、斯洛文尼亚)、亚洲(中国、韩国)和南美(巴西)的临床健康马匹中检测到。以前在世界范围内进行的流行病学研究表明,血清或血浆中EqPV-H DNA的含量在3.2%至19.8%之间。本研究调查了位于加拿大安大略省南部37个农场的170只不同品种的健康母马eqpvh DNA的流行情况。采用血清中EqPV-H DNA的定量PCR检测感染情况。研究了年龄、品种、季节、妊娠状况和马疱疹病毒-1 (EHV-1)疫苗接种史对EqPV-H状态的影响。EqPV-H病毒载量范围从可检测到2900拷贝/mL,患病率为15.9%(27/170)。统计分析表明,年龄的增加是影响EqPV-H DNA检测的显著因素。在预测EqPV-H感染状况方面,品种、季节、妊娠状况和EHV-1疫苗接种史均无显著意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence of equine parvovirus-hepatitis in healthy broodmares in Ontario, Canada.

Equine parvovirus-hepatitis (EqPV-H) was first reported from the serum and liver tissue of a horse diagnosed with Theiler's disease in the United States in 2018. Theiler's disease, also known as equine serum hepatitis, is a severe hepatitis with fulminant hepatic necrosis. The disease has most frequently been reported following the administration of equine-origin biological products; however, it has also been reported in in-contact horses with no prior biologic administration. EqPV-H has been detected in clinically healthy horses in North America (USA, Canada), Europe (Germany, Austria, Slovenia), Asia (China, South Korea), and South America (Brazil). Previous prevalence studies conducted worldwide have shown the presence of EqPV-H DNA in serum or plasma ranging from 3.2 to 19.8%. This study investigated the prevalence of EqPV-H DNA in 170 healthy broodmares of various breeds located on 37 farms in southern Ontario, Canada. The occurrence of EqPV-H infection was determined by quantitative PCR for EqPV-H DNA in serum samples. The effects of age, breed, season, pregnancy status, and equine herpesvirus-1 (EHV-1) vaccination history on EqPV-H status were also investigated. There was a prevalence of 15.9% (27/170) with viral loads of EqPV-H ranging from detectable to 2900 copies/mL. Statistical analysis showed that increasing age was a significant factor in the detection of EqPV-H DNA. Neither breed, season, pregnancy status, nor EHV-1 vaccination history was significant in predicting EqPV-H infection status.

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来源期刊
CiteScore
1.80
自引率
0.00%
发文量
58
审稿时长
>24 weeks
期刊介绍: The Canadian Journal of Veterinary Research, published by the Canadian Veterinary Medical Association, is Canada''s only veterinary research publication. This quarterly peer-reviewed online-only journal has earned a wide international readership through the publishing of high quality scientific papers in the field of veterinary medicine. The Journal publishes the results of original research in veterinary and comparative medicine.
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