空气质量对10-12岁学龄儿童睡眠和认知表现的影响:一项双盲、安慰剂对照、交叉试验

IF 1.4 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Frida Bejder Klausen, Ali Amidi, Søren K Kjærgaard, Vivi Schlünssen, Peter Ravn, Kirsten Østergaard, Vibeke Heitmann Gutzke, Marianne Glasius, Therese Koops Grønborg, Stefan Nygaard Hansen, Robert Zachariae, Pawel Wargocki, Torben Sigsgaard
{"title":"空气质量对10-12岁学龄儿童睡眠和认知表现的影响:一项双盲、安慰剂对照、交叉试验","authors":"Frida Bejder Klausen,&nbsp;Ali Amidi,&nbsp;Søren K Kjærgaard,&nbsp;Vivi Schlünssen,&nbsp;Peter Ravn,&nbsp;Kirsten Østergaard,&nbsp;Vibeke Heitmann Gutzke,&nbsp;Marianne Glasius,&nbsp;Therese Koops Grønborg,&nbsp;Stefan Nygaard Hansen,&nbsp;Robert Zachariae,&nbsp;Pawel Wargocki,&nbsp;Torben Sigsgaard","doi":"10.13075/ijomeh.1896.02032","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the effect of CO<sub>2</sub> during sleep on next-morning cognitive performance in young schoolchildren, the authors performed a double-blind fully balanced crossover placebo-controlled study.</p><p><strong>Material and methods: </strong>The authors included 36 children aged 10-12 years in the climate chamber. The children slept at 21°C in 6 groups each at 3 different conditions separated by 7 days in a random order. Conditions were as follows: high ventilation with CO<sub>2</sub> at 700 ppm, high ventilation with added pure CO<sub>2</sub> at 2000-3000 ppm, and reduced ventilation with CO<sub>2</sub> at 2-3000 ppm and bioeffluents. Children were subjected to a digital cognitive test battery (CANTAB) in the evening prior to sleep and on the next morning after breakfast. Sleep quality was monitored with wrist actigraphs.</p><p><strong>Results: </strong>There were no significant exposure effects on cognitive performance. Sleep efficiency was significantly lower at high ventilation with CO<sub>2</sub> at 700 ppm which is considered to be a chance effect. No other effects were seen, and no relation between air quality during sleep and next-morning cognitive performance was observed in the children emitting an estimated 10 l<sub>CO<sub>2</sub></sub>/h per child.</p><p><strong>Conclusions: </strong>No effect of CO<sub>2</sub> during sleep was found on next day cognition. The children were awakened in the morning, and spent from 45-70 min in well-ventilated rooms before they were tested. Hence, it cannot be precluded that the children have benefitted from the good indoor air quality conditions before and during the testing period. The slightly better sleep efficiency during high CO<sub>2</sub> concentrations might be a chance finding. Hence, replication is needed in actual bedrooms controlling for other external factors before any generalizations can be made. Int J Occup Med Environ Health. 2023;36(2):177-91.</p>","PeriodicalId":14173,"journal":{"name":"International journal of occupational medicine and environmental health","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0e/d7/ijomeh-36-177.PMC10464806.pdf","citationCount":"3","resultStr":"{\"title\":\"The effect of air quality on sleep and cognitive performance in school children aged 10-12 years: a double-blinded, placebo-controlled, crossover trial.\",\"authors\":\"Frida Bejder Klausen,&nbsp;Ali Amidi,&nbsp;Søren K Kjærgaard,&nbsp;Vivi Schlünssen,&nbsp;Peter Ravn,&nbsp;Kirsten Østergaard,&nbsp;Vibeke Heitmann Gutzke,&nbsp;Marianne Glasius,&nbsp;Therese Koops Grønborg,&nbsp;Stefan Nygaard Hansen,&nbsp;Robert Zachariae,&nbsp;Pawel Wargocki,&nbsp;Torben Sigsgaard\",\"doi\":\"10.13075/ijomeh.1896.02032\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>To investigate the effect of CO<sub>2</sub> during sleep on next-morning cognitive performance in young schoolchildren, the authors performed a double-blind fully balanced crossover placebo-controlled study.</p><p><strong>Material and methods: </strong>The authors included 36 children aged 10-12 years in the climate chamber. The children slept at 21°C in 6 groups each at 3 different conditions separated by 7 days in a random order. Conditions were as follows: high ventilation with CO<sub>2</sub> at 700 ppm, high ventilation with added pure CO<sub>2</sub> at 2000-3000 ppm, and reduced ventilation with CO<sub>2</sub> at 2-3000 ppm and bioeffluents. Children were subjected to a digital cognitive test battery (CANTAB) in the evening prior to sleep and on the next morning after breakfast. Sleep quality was monitored with wrist actigraphs.</p><p><strong>Results: </strong>There were no significant exposure effects on cognitive performance. Sleep efficiency was significantly lower at high ventilation with CO<sub>2</sub> at 700 ppm which is considered to be a chance effect. No other effects were seen, and no relation between air quality during sleep and next-morning cognitive performance was observed in the children emitting an estimated 10 l<sub>CO<sub>2</sub></sub>/h per child.</p><p><strong>Conclusions: </strong>No effect of CO<sub>2</sub> during sleep was found on next day cognition. The children were awakened in the morning, and spent from 45-70 min in well-ventilated rooms before they were tested. Hence, it cannot be precluded that the children have benefitted from the good indoor air quality conditions before and during the testing period. The slightly better sleep efficiency during high CO<sub>2</sub> concentrations might be a chance finding. Hence, replication is needed in actual bedrooms controlling for other external factors before any generalizations can be made. Int J Occup Med Environ Health. 2023;36(2):177-91.</p>\",\"PeriodicalId\":14173,\"journal\":{\"name\":\"International journal of occupational medicine and environmental health\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2023-05-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0e/d7/ijomeh-36-177.PMC10464806.pdf\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International journal of occupational medicine and environmental health\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.13075/ijomeh.1896.02032\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International journal of occupational medicine and environmental health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.13075/ijomeh.1896.02032","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 3

摘要

目的:为了研究睡眠期间二氧化碳对小学生第二天早晨认知表现的影响,作者进行了一项双盲、完全平衡的交叉安慰剂对照研究。材料和方法:作者将36名10-12岁的儿童纳入气候室。孩子们在21°C的环境下睡眠,分为6组,每组有3种不同的条件,随机间隔7天。条件如下:二氧化碳浓度为700 ppm时的高通风,添加2000-3000 ppm纯二氧化碳时的高通风,以及二氧化碳浓度为2-3000 ppm和生物污水时的低通风。孩子们在晚上睡觉前和第二天早上早餐后接受了数字认知测试(CANTAB)。睡眠质量通过腕动仪监测。结果:暴露对认知表现无显著影响。在二氧化碳含量为700 ppm的高通风条件下,睡眠效率明显较低,这被认为是一个偶然效应。没有观察到其他影响,睡眠期间的空气质量和第二天早上的认知表现之间没有关系,在这些儿童中,估计每个孩子每小时排放10 lCO2。结论:睡眠时二氧化碳对次日认知无影响。孩子们在早上被叫醒,在进行测试之前在通风良好的房间里待45-70分钟。因此,不能排除儿童在测试前和测试期间受益于良好的室内空气质量条件。在二氧化碳浓度高的情况下,睡眠效率略有提高可能是一个偶然的发现。因此,在得出任何结论之前,需要在实际卧室中进行复制,控制其他外部因素。中华医学杂志,2009;36(2):377 - 391。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The effect of air quality on sleep and cognitive performance in school children aged 10-12 years: a double-blinded, placebo-controlled, crossover trial.

The effect of air quality on sleep and cognitive performance in school children aged 10-12 years: a double-blinded, placebo-controlled, crossover trial.

The effect of air quality on sleep and cognitive performance in school children aged 10-12 years: a double-blinded, placebo-controlled, crossover trial.

The effect of air quality on sleep and cognitive performance in school children aged 10-12 years: a double-blinded, placebo-controlled, crossover trial.

Objectives: To investigate the effect of CO2 during sleep on next-morning cognitive performance in young schoolchildren, the authors performed a double-blind fully balanced crossover placebo-controlled study.

Material and methods: The authors included 36 children aged 10-12 years in the climate chamber. The children slept at 21°C in 6 groups each at 3 different conditions separated by 7 days in a random order. Conditions were as follows: high ventilation with CO2 at 700 ppm, high ventilation with added pure CO2 at 2000-3000 ppm, and reduced ventilation with CO2 at 2-3000 ppm and bioeffluents. Children were subjected to a digital cognitive test battery (CANTAB) in the evening prior to sleep and on the next morning after breakfast. Sleep quality was monitored with wrist actigraphs.

Results: There were no significant exposure effects on cognitive performance. Sleep efficiency was significantly lower at high ventilation with CO2 at 700 ppm which is considered to be a chance effect. No other effects were seen, and no relation between air quality during sleep and next-morning cognitive performance was observed in the children emitting an estimated 10 lCO2/h per child.

Conclusions: No effect of CO2 during sleep was found on next day cognition. The children were awakened in the morning, and spent from 45-70 min in well-ventilated rooms before they were tested. Hence, it cannot be precluded that the children have benefitted from the good indoor air quality conditions before and during the testing period. The slightly better sleep efficiency during high CO2 concentrations might be a chance finding. Hence, replication is needed in actual bedrooms controlling for other external factors before any generalizations can be made. Int J Occup Med Environ Health. 2023;36(2):177-91.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
3.40
自引率
5.00%
发文量
52
审稿时长
7.5 months
期刊介绍: The Journal is dedicated to present the contemporary research in occupational and environmental health from all over the world. It publishes works concerning: occupational and environmental: medicine, epidemiology, hygiene and toxicology; work physiology and ergonomics, musculoskeletal problems; psychosocial factors at work, work-related mental problems, aging, work ability and return to work; working hours, shift work; reproductive factors and endocrine disruptors; radiation, ionizing and non-ionizing health effects; agricultural hazards; work safety and injury and occupational health service; climate change and its effects on health; omics, genetics and epigenetics in occupational and environmental health; health effects of exposure to nanoparticles and nanotechnology products; human biomarkers in occupational and environmental health, intervention studies, clinical sciences’ achievements with potential to improve occupational and environmental health.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信