圈养猕猴(Macaca Mulatta)的自发性白癜风。

IF 1.3 4区农林科学 Q2 VETERINARY SCIENCES

Comparative medicine Pub Date : 2023-06-01 DOI:10.30802/AALAS-CM-22-000091

Bárbara Cs Meireles, Beatriz Goldschmidt, Cláudia A Lopes, Kelly C Demarque, Gabriel M Leal, Mariana S Magalhães, Milena B Souza, Ricardo S Cruz

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引用次数: 0

摘要

白癜风影响着人类和动物种群的很大一部分。由于黑色素细胞的丢失或缺失，该疾病导致毛皮、皮肤和粘膜色素沉着的不规则和多灶性进行性丧失。虽然病因尚不完全清楚，但涉及自身免疫、环境和遗传因素。我们报告了一例16岁雌性恒河猴(Macaca mulatta)的病例报告，其皮肤和皮毛上的色素脱色区域逐渐增加，并分布在头部和背部。组织病理学显示与白癜风相一致的改变，其特征是表皮和真皮中缺乏黑色素细胞。临床病史和辅助检查支持这一诊断。

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Spontaneous Vitiligo in a Captive Rhesus Monkey (Macaca Mulatta).

Vitiligo affects a significant portion of human and animal populations. The disease causes irregular and multifocal progressive loss of fur, skin, and mucous membrane pigmentation due to the loss or absence of melanocytes. While etiopathogenesis is not completely understood, autoimmunity, environmental, and genetic factors are implicated We present a case report on a 16-y-old female rhesus macaque (Macaca mulatta ) with depigmented areas that are progressively increasing on the skin and coat and are distributed on the head and back. Histopathology revealed alterations compatible with vitiligo characterized by the absence of melanocytes in the epidermis and dermis. The clinical history and complementary exams support this diagnosis.

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来源期刊

Comparative medicine 医学-动物学

CiteScore

1.90

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Comparative Medicine (CM), an international journal of comparative and experimental medicine, is the leading English-language publication in the field and is ranked by the Science Citation Index in the upper third of all scientific journals. The mission of CM is to disseminate high-quality, peer-reviewed information that expands biomedical knowledge and promotes human and animal health through the study of laboratory animal disease, animal models of disease, and basic biologic mechanisms related to disease in people and animals.