使用间充质干细胞提取的外泌体进行治疗：再生医学治疗科学的新窗口。

IF 2.1 4区医学 Q4 CELL & TISSUE ENGINEERING

Current stem cell research & therapy Pub Date : 2024-01-01 DOI:10.2174/1574888X18666230824165014

Arezoo Hormozi, Sajedeh Hasanzadeh, Faezeh Ebrahimi, Narges Daei, Zahra Hajimortezayi, Amir Mehdizadeh, Majid Zamani

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引用次数: 0

摘要

近年来，由于间充质干细胞（MSC）在再生医学中的重要性与日俱增，有关间充质干细胞潜在应用的研究层出不穷。外泌体被认为是能够运输蛋白质、肽、脂质、mRNA 和生长因子的载体。间充质干细胞衍生的外泌体还参与了多种疾病的预防或治疗，包括心血管疾病、神经系统疾病、皮肤疾病、肺部疾病、骨关节炎、受损组织修复和其他疾病。本综述试图通过收集和评估现有文献中的信息，总结在再生医学中使用间充质干细胞的重要性。此外，还讨论了间充质干细胞的作用以及间充质干细胞衍生外泌体的潜在应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Treatment with Exosomes Derived from Mesenchymal Stem Cells: A New Window of Healing Science in Regenerative Medicine.

Many studies have been conducted on the potential applications of mesenchymal stem cells (MSCs) over recent years due to their growing importance in regenerative medicine. Exosomes are considered cargos capable of transporting proteins, peptides, lipids, mRNAs, and growth factors. MSCsderived exosomes are also involved in the prevention or treatment of a variety of diseases, including cardiovascular diseases, neurological diseases, skin disorders, lung diseases, osteoarthritis, damaged tissue repair, and other diseases. This review attempted to summarize the importance of employing MSCs in regenerative medicine by gathering and evaluating information from current literature. The role of MSCs and the potential applications of MSCs-derived exosomes have also been discussed.

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来源期刊

Current stem cell research & therapy CELL & TISSUE ENGINEERING-CELL BIOLOGY

CiteScore

4.20

自引率

3.70%

发文量

197

审稿时长

>12 weeks

期刊介绍： Current Stem Cell Research & Therapy publishes high quality frontier reviews, drug clinical trial studies and guest edited issues on all aspects of basic research on stem cells and their uses in clinical therapy. The journal is essential reading for all researchers and clinicians involved in stem cells research.