肿瘤诱导的骨质减少是由于磷酸-间充质鼻窦肿瘤表现为迟发性功能不全性骨折。

IF 0.7 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Journal of Radiology Case Reports Pub Date : 2023-07-31 eCollection Date: 2023-07-01 DOI:10.3941/jrcr.v17i7.4912
Freda Jawan, Weiling Lim, Joe Francis
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引用次数: 0

摘要

我们报告一例48岁女性鼻出血。磁共振成像(MRI)显示左鼻腔内有一个肿块,被发现是一个磷酸间充质鼻窦肿瘤。该患者在此阶段未接受治疗,后来再次出现骨盆和腹股沟疼痛,平片和计算机断层扫描显示不同年龄的弥漫性骨质减少和多发性骨盆骨折。骨盆和大腿两侧的核磁共振成像显示骨骼的骨髓信号异常,并证实了骨盆骨折的存在。股骨和肩胛骨多处假性骨折。放射学检查结果和异常生化标志物被归因于肿瘤诱导的骨软化的副肿瘤实体,在未切除的磷尿质间充质肿瘤的背景下。肿瘤被切除,患者表现出相关生化异常的完全逆转。该病例表明,早期发现并完全切除病因肿瘤,预后良好。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Tumour induced osteopenia due to phosphaturic mesenchymal sinonasal tumour presenting with delayed onset insufficiency fractures.

We present a case of a 48-year-old female who presented with epistaxis. Magnetic resonance imaging (MRI) revealed a mass within the left nasal cavity which was revealed to be a phosphaturic mesenchymal sinonasal tumour. The patient defaulted treatment at this stage and later re-presented with pelvic and groin pain for which plain radiographs and computed tomography (CT) scan demonstrated diffuse osteopenia and multiple pelvic fractures of varying ages. MRI of the pelvis and both thighs revealed abnormal marrow signal of the bones and confirmed the presence of pelvic fractures. Multiple pseudo-fractures were seen at both femurs and scapula. The radiological findings along with abnormal biochemical markers were attributed to the paraneoplastic entity of tumour induced osteomalacia, in the context of unresected phosphaturic mesenchymal tumour. The tumour was resected, and patient showed complete reversal of the associated biochemical abnormalities. This case exemplifies that with early identification and complete resection of the causative tumour, the prognosis is excellent.

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来源期刊
Journal of Radiology Case Reports
Journal of Radiology Case Reports RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
1.10
自引率
0.00%
发文量
25
审稿时长
24 weeks
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