伊朗的胃病:社会和经济因素在幽门螺杆菌感染中的作用。

IF 2.4 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Hamed Zandian, Telma Zahirian Moghadam, Farhad Pourfarzi, Reza Malekzadeh, Satar Rezaei, Sevda Ghorbani
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引用次数: 0

摘要

背景:幽门螺杆菌感染是伊朗胃癌的主要危险因素,但社会经济因素对其患病率的影响尚不清楚。本研究旨在评估伊朗社会经济不平等和与幽门螺杆菌感染相关的危险因素。方法:本横断面研究在波斯队列研究的基础上进行。伊朗阿达比勒共有20460名年龄在35岁至70岁之间的人参与了这项研究。根据粪便检查和临床记录确定幽门螺杆菌感染。采用家庭和社区水平随机截取的多水平logistic回归模型来确定与幽门螺杆菌患病率相关的危险因素。浓度指数(CIn)和浓度曲线(CC)被用来评估社会经济相关的不平等。结果:在本研究中,70.4% (CI 69.6-71.0)的参与者感染了幽门螺杆菌,女性患病率(71.2%)高于男性(69.6%)。多变量logistic回归结果显示,年龄(OR: 1.37, CI: 1.17-1.61)、性别(OR: 1.20, CI: 1.12-1.28)、教育水平(OR: 1.33, CI: 1.17-1.49)、心脏病(OR: 1.32, CI:1.18-1.46)和BMI组(OR: 2.49, CI: 1.11-5.58)与幽门螺杆菌感染显著相关。CIn和CC结果表明,幽门螺杆菌在经济条件较差的人群中更为普遍(CIn: -0.1065;[-0.1374至-0.0755])。结论:伊朗幽门螺杆菌患病率高于其他发展中国家,贫富差距明显。为了降低胃癌的发病率,应考虑社会经济和人口因素,特别是穷人和受教育程度低的人。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Gastric troubles in Iran: The role of social and economic factors in <i>Helicobacter pylori</i> infection.

Gastric troubles in Iran: The role of social and economic factors in <i>Helicobacter pylori</i> infection.

Gastric troubles in Iran: The role of social and economic factors in Helicobacter pylori infection.

Background: Helicobacter pylori infection is a major risk factor for gastric cancer in Iran, but the impact of socioeconomic factors on its prevalence is poorly understood. This study aimed to assess the socioeconomic inequalities and risk factors associated with H. pylori infection in Iran.

Methods: This cross-sectional study was conducted based on the PERSIAN cohort study. A total of 20460 individuals aged 35 to 70 years in Ardabil, Iran were included in the study. H. pylori infection was determined based on stool tests and clinical records. Multilevel logistic regression models with random intercepts at household and community levels were used to identify risk factors associated with H. pylori prevalence. The concentration index (CIn) and concentration curve (CC) were employed to assess socioeconomic-related inequality.

Results: In this study, 70.4% (CI 69.6-71.0) of the participants were infected with H. pylori, with a higher prevalence in women (71.2%) than men (69.6%). Age (OR: 1.37, CI: 1.17-1.61), sex (OR: 1.20, CI: 1.12-1.28), level of education (OR: 1.33, CI: 1.17-1.49), cardiac disease (OR: 1.32, CI:1.18-1.46), and BMI groups (OR: 2.49, CI: 1.11-5.58) were significantly associated with H. pylori infection based on the multivariable logistic regression. The results of the CIn and CC indicated that H. pylori were more prevalent among economically disadvantaged groups (CIn: -0.1065; [-0.1374 to -0.0755]).

Conclusion: The prevalence of H. pylori in Iran is higher than in other developing countries, and significant socioeconomic inequality exists between the poor and the rich. To reduce the rate of gastric cancer, socio-economic and demographic factors, especially the poor and people with low levels of education, should be considered.

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来源期刊
Health Promotion Perspectives
Health Promotion Perspectives PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
7.10
自引率
2.30%
发文量
27
审稿时长
13 weeks
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