HIGH-FIBER DIET PROMOTES METABOLIC, HORMONAL, AND SATIETY EFFECTS IN OBESE WOMEN ON A SHORT-TERM CALORIC RESTRICTION.

Q2 Medicine
Andresa de Toledo Triffoni-Melo, Margaret de Castro, Alceu Afonso Jordão, Vânia Aparecida Leandro-Merhi, Ingrid Dick-DE-Paula, Rosa Wanda Diez-Garcia
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引用次数: 0

Abstract

•Body weight and BMI decrease in both the EG and CG groups during the period of caloric restriction. •For both the EG and CG groups, fat-free mass decreases during food restriction. •Subjects on a high-fiber diet have reduced fasting glucose and basal insulin as well as improved insulin resistance, as attested by the lower HOMA-IR index. •Obese women on a high-fiber diet have suppressed postprandial (after 60 min) acylated ghrelin, confirming that the diet composition influences ghrelin levels from the first day. •In the present study, it was possible to verify that fasting leptin concentration diminishes in obese women on a high-fiber diet. Background - Several mechanisms, including excessive hunger, account for patients' difficulties in maintaining weight loss and dietary changes after caloric restriction. Objective - To evaluate the effect of short-term high-fiber calorie-restricted diet in appetite-regulating hormones, and hunger and satiety sensations in women with obesity. In a randomized controlled trial study, thirty women with body mass index (BMI) higher than 30 kg/m2, and aged from 20 to 50 years were hospitalized following a calorie-restricted diet (1000 kcal/day) for three days. The experimental group (n=15) received high-fiber diet and the control group (n=15), conventional diet. Results - Body weight, BMI, resting energy expenditure (REE), acylated and total ghrelin, leptin, insulin and glucose, and hunger and satiety sensations were evaluated. Linear regression models with mixed effects (fixed and random effects) helped to assess the variables between the two groups and within the groups. Body weight and BMI decreased in both the experimental and control groups (P<0.001). After the high-fiber diet, postprandial acylated ghrelin (P=0.04), glucose (P<0.001), insulin (P=0.04), and leptin (P=0.03) levels as well as the HOMA-IR index (P=0.01) decreased, whereas satiety improved (P=0.02). Obese women that followed the conventional diet had increased body fat percentage (P=0.04) and lower REE (P=0.02). The two diets did not differ in terms of hunger sensation. Conclusion - A short-term high-fiber diet improves satiety sensations and metabolic parameters while suppressing postprandial acylated ghrelin (60 minutes) and maintaining the resting energy expenditure.

高纤维饮食可以促进短期热量限制下肥胖女性的代谢、激素和饱腹感。
•在热量限制期间,EG组和CG组的体重和BMI都有所下降。•对于EG和CG组,在食物限制期间,无脂肪质量都会降低。•高纤维饮食的受试者空腹血糖和基础胰岛素降低,胰岛素抵抗改善,HOMA-IR指数降低证明了这一点。•高纤维饮食的肥胖女性在餐后(60分钟后)抑制了酰化胃饥饿素,证实饮食成分从第一天起就影响胃饥饿素水平。•在本研究中,有可能证实高纤维饮食的肥胖女性空腹瘦素浓度降低。背景-一些机制,包括过度饥饿,解释了患者在热量限制后难以保持体重减轻和饮食变化的原因。目的:评价短期高纤维热量限制饮食对肥胖女性食欲调节激素、饥饿感和饱腹感的影响。在一项随机对照试验研究中,30名体重指数(BMI)高于30 kg/m2、年龄在20至50岁之间的女性在接受热量限制饮食(1000 kcal/天)后住院三天。实验组(n=15)接受高纤维饮食,对照组(n=5)接受常规饮食。结果:评估了体重、BMI、静息能量消耗(REE)、酰化和总胃饥饿素、瘦素、胰岛素和葡萄糖以及饥饿感和饱腹感。具有混合效应(固定效应和随机效应)的线性回归模型有助于评估两组之间和组内的变量。实验组和对照组的体重和BMI均有所下降(P
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来源期刊
Arquivos de Gastroenterologia
Arquivos de Gastroenterologia Medicine-Gastroenterology
CiteScore
2.00
自引率
0.00%
发文量
109
审稿时长
9 weeks
期刊介绍: The journal Arquivos de Gastroenterologia (Archives of Gastroenterology), a quarterly journal, is the Official Publication of the Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia IBEPEGE (Brazilian Institute for Studies and Research in Gastroenterology), Colégio Brasileiro de Cirurgia Digestiva - CBCD (Brazilian College of Digestive Surgery) and of the Sociedade Brasileira de Motilidade Digestiva - SBMD (Brazilian Digestive Motility Society). It is dedicated to the publishing of scientific papers by national and foreign researchers who are in agreement with the aim of the journal as well as with its editorial policies.
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