SWEET'S SYNDROME IN A PATIENT WITH CROHN DISEASE: A CASE REPORT.

Abstract

Sweet’s syndrome, or acute febrile neutrophilic dermatoses, was first described in 1964 by Robert Douglas Sweet (Neoh, Tan, & Ng, 2007). Sweet’s syndrome is more common in females, with a female to male ratio of 3.7:1, and a mean age of 52 years (Cohen, 2007). This syndrome presents with fever, neutrophil-dominant leukocytosis, red– brown plaques, and nodules mainly in the head, neck, and upper extremities, which are painful and tender to touch. Crohn disease (CD) is an immunity-based inflammatory disease with unknown etiology that may affect any part of the gastrointestinal tract with a transmural pattern of inflammation (Stange et al., 2006). Cutaneous manifestations of CD are usually erythema nodosum, oral aphthous ulcers, and epidermolysis bullosa. On the other hand, Sweet’s syndrome is rarely associated with CD (Trost & McDonnell, 2005).