Utilization of European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 scale for evaluation of quality of life among cancer patients treated with chemotherapy: A hospital-based observational study.

IF 1 4区 医学 Q4 ONCOLOGY
Journal of Oncology Pharmacy Practice Pub Date : 2024-07-01 Epub Date: 2023-08-03 DOI:10.1177/10781552231189706
Manjula Gudhoor, Aneetta Thankam Mathew, Akul Madiwalayya Ganachari, Gayathri Baiju, Sushrut Sachchidanand Kulkarni, M S Ganachari
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引用次数: 0

Abstract

Background: In this new era of cancer management, the quality of life (QOL) is given more importance than the quantity of life. QOL evaluation studies are widely used in oncology to assess the patient's performance in different cancer types and treatment modalities.

Objective: To evaluate cancer patients' QOL after various chemotherapy cycles.

Methods: An observational study was performed on cancer patients receiving chemotherapy in the daycare setting of a South Indian Tertiary Care Hospital for 6 months. European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) questionnaire was employed to study the QOL.

Results: Precisely, 102 patients participated in the study, out of which the majority were in the 51 to 60 age group (24%). Female participants (65%) were more. Functional scale domains especially physical ability (P = 0.004), role (P = 0.033), and emotional functioning (P = 0.01) were significantly decreased in patients treated with 4 to 6 chemotherapy cycles. Cognitive ability (P = 0.043) significantly improved in patients treated with more than 6 chemotherapy cycles. Dyspnea (P = 0.036) was significantly increased in patients treated with 4 to 6 chemotherapy cycles and decreased significantly with the further addition of chemotherapy cycles.

Conclusion: Dyspnea is a commonly observed symptom among cancer patients and is often neglected by physicians. Chronic dyspnea can negatively impact a patient's functional ability. Cancer symptoms such as dyspnea should also be given priority and need appropriate treatment. Based on the findings, further interventions can be made to improve the functional ability of cancer patients. Also, studies can be conducted to correlate with cancer rehabilitation programs to improve functional ability and complete the entire chemotherapy cycle.

利用欧洲癌症研究和治疗组织生活质量问卷--核心 30 量表评估接受化疗的癌症患者的生活质量:一项基于医院的观察研究。
背景:在癌症治疗的新时代,生活质量(QOL)比生活数量更受重视。QOL评估研究被广泛应用于肿瘤学领域,以评估患者在不同癌症类型和治疗方式下的表现:评估癌症患者在不同化疗周期后的 QOL:方法:对在南印度一家三级医院日间护理中心接受化疗的癌症患者进行为期 6 个月的观察研究。研究采用了欧洲癌症研究和治疗组织生活质量问卷-核心 30(EORTC QLQ-C30)调查问卷:确切地说,共有 102 名患者参与了研究,其中大多数患者年龄在 51 至 60 岁之间(24%)。女性参与者(65%)更多。接受 4 至 6 个化疗周期治疗的患者的功能量表领域,尤其是体能(P = 0.004)、角色(P = 0.033)和情感功能(P = 0.01)显著下降。接受超过 6 个化疗周期治疗的患者认知能力(P = 0.043)明显提高。呼吸困难(P = 0.036)在接受4至6个化疗周期治疗的患者中明显增加,并随着化疗周期的增加而明显减少:结论:呼吸困难是癌症患者常见的症状,但往往被医生忽视。长期呼吸困难会对患者的功能造成负面影响。呼吸困难等癌症症状也应得到重视,并需要适当的治疗。根据研究结果,可以采取进一步的干预措施来改善癌症患者的功能能力。此外,还可以开展与癌症康复计划相关的研究,以提高患者的功能能力并完成整个化疗周期。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
2.70
自引率
7.70%
发文量
276
期刊介绍: Journal of Oncology Pharmacy Practice is a peer-reviewed scholarly journal dedicated to educating health professionals about providing pharmaceutical care to patients with cancer. It is the official publication of the International Society for Oncology Pharmacy Practitioners (ISOPP). Publishing pertinent case reports and consensus guidelines...
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