Lateral ventricle subependymoma resected with a transcallosal approach: illustrative case.

Franco Rubino, Michael P Catalino, Romulo A Andrade de Almeida, Sujit S Prabhu
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Abstract

Background: Subependymomas are World Health Organization grade I tumors, and 30% occur in the lateral ventricles. Surgery is the mainstay of treatment, and the transcallosal or transcortical/transsulcal approaches are preferred for those tumors occurring near the foramen of Monro or atrium. Visualization, proximity to the fornix and basal ganglia, hydrocephalus, and brain retraction during surgery make these operations challenging. The authors present the case of a 65-year-old male with a subependymoma located in the left lateral ventricle. The tumor was completely resected using an interhemispheric/transcallosal approach.

Observations: The authors analyze the anatomopathological features of subependymoma, along with the clinical behavior and therapeutic options. The authors discuss in detail the advantages and disadvantages of the interhemispheric/transcallosal approach for resection of these tumors.

Lessons: Subependymomas are slow-growing lesions with an indolent yet complicated course making surgical removal challenging yet feasible using the correct techniques. The interhemispheric transcallosal approach offers an excellent route for the resection of large subependymomas, but there is still a significant risk for postoperative complications.

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经同种异体骨入路切除侧脑室室管膜下瘤:一例说明性病例。
背景:室管膜下瘤是世界卫生组织的一级肿瘤,30%发生在侧脑室。手术是治疗的主要手段,对于发生在门罗孔或心房附近的肿瘤,首选经异体骨或经皮质/经溃疡入路。手术过程中的可视化、接近穹窿和基底神经节、脑积水和大脑回缩使这些手术具有挑战性。作者报告了一例65岁男性,左心室室管膜下瘤。肿瘤采用半球间/经同种异体骨入路完全切除。观察:作者分析了室管膜下瘤的解剖病理特征,以及临床行为和治疗选择。作者详细讨论了半球间/经同种异体骨入路切除这些肿瘤的优缺点。经验教训:室管膜下瘤是生长缓慢的病变,病程缓慢但复杂,使用正确的技术进行手术切除具有挑战性但可行。半球间经同种异体骨入路为切除大型室管膜下瘤提供了一条极好的途径,但术后并发症的风险仍然很大。
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