Intralesional bleomycin injection treatment of intra-abdominal lymphangiomas presenting with acute abdomen in children.

IF 0.8 4区 医学 Q4 EMERGENCY MEDICINE
Rahşan Özcan, Ali Ekber Hakalmaz, Senol Emre, Ayten Ceren Bakır, Süreyya Aydın, Fatih Gulsen, Osman Faruk Senyuz, Gonca Topuzlu Tekant
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Abstract

Background: We evaluated the results of urgent intralesional bleomycin injection (IBI) treatment of intra-abdominal lymphan-giomas (IAL) presenting with acute abdomen in children.

Methods: The records of patients who underwent urgent IBI due to acutely presenting IAL between January 2013 and January 2020 were reviewed retrospectively in terms of age, presenting symptoms, cyst type, number of injections, pre- and post-treatment cyst volume, clinical response, complications, and follow-up.

Results: Six patients with a mean age of 4.3 years (2-13 years) were treated. Presenting symptoms were acute abdominal pain (n=4), abdominal distention (n=1), hypoproteinemia and chylous ascites (n=1). Lesions were of macrocystic type in four and macro and micro cystic in two patients. The median number of injections performed was 2 (1-11). Mean cyst volume reduced dramatically from 567 cm3 (range 117-1656) to 3.4 cm3 (range 0-13.8) after treatment (p=0.028). Treatment response was excellent in four patients with complete resolution of the cysts, while good in the remaining two. No early or late complications or recurrence was observed in a mean follow-up period of 40 months (16-56 months).

Conclusion: IBI is a safe, fast, and easily applicable method with satisfactory results in the treatment of acutely presenting IAL. It may be recommended in primary as well as recurrent lesions.

Abstract Image

Abstract Image

病灶内注射博来霉素治疗以急腹症为表现的小儿腹腔内淋巴管瘤。
背景:我们评估了紧急病灶内注射博来霉素(IBI)治疗以急腹症为表现的儿童腹腔淋巴组织瘤(IAL)的结果。方法:回顾性分析2013年1月至2020年1月期间因急性表现IAL而行紧急IBI的患者的年龄、症状、囊肿类型、注射次数、治疗前后囊肿体积、临床反应、并发症和随访情况。结果:治疗6例患者,平均年龄4.3岁(2 ~ 13岁)。表现为急性腹痛(n=4)、腹胀(n=1)、低蛋白血症和乳糜腹水(n=1)。大囊型病变4例,大、微囊型病变2例。注射次数中位数为2次(1-11次)。治疗后平均囊肿体积从567 cm3(范围117-1656)急剧减少到3.4 cm3(范围0-13.8)(p=0.028)。4例患者的治疗效果非常好,囊肿完全消退,其余2例良好。平均随访40个月(16 ~ 56个月),无早期、晚期并发症及复发。结论:IBI是一种安全、快速、简便的治疗急性IAL的方法,疗效满意。它可能被推荐用于原发性和复发性病变。
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来源期刊
CiteScore
1.40
自引率
18.20%
发文量
82
审稿时长
4-8 weeks
期刊介绍: The Turkish Journal of Trauma and Emergency Surgery (TJTES) is an official publication of the Turkish Association of Trauma and Emergency Surgery. It is a double-blind and peer-reviewed periodical that considers for publication clinical and experimental studies, case reports, technical contributions, and letters to the editor. Scope of the journal covers the trauma and emergency surgery. Each submission will be reviewed by at least two external, independent peer reviewers who are experts in their fields in order to ensure an unbiased evaluation process. The editorial board will invite an external and independent reviewer to manage the evaluation processes of manuscripts submitted by editors or by the editorial board members of the journal. The Editor in Chief is the final authority in the decision-making process for all submissions.
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