Stroke and its correlates among patients on maintenance hemodialysis in Cameroon

IF 1.2 4区医学 Q3 UROLOGY & NEPHROLOGY

Hemodialysis International Pub Date : 2023-06-01 DOI:10.1111/hdi.13097

Denis Georges Teuwafeu, Marie Patrice Halle, Nadine Aurore Kenfack, Cyrille Duquesne Nkouonlack, Hermine Fouda, Clovis Nkoke, Yacouba Mapoure Njankouo

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引用次数: 0

Abstract

Background

End-stage kidney disease is an independent risk factor for stroke; however, the relationship between hemodialysis and stroke in Sub-Saharan Africa has not been established.

Objective

To evaluate the incidence, associated factors, and clinical outcome of stroke among patients undergoing maintenance hemodialysis in Cameroon.

Methods

A hospital-based retrospective study using data from the medical files of 1060 patients on maintenance hemodialysis (given twice a week) was conducted. Patients with stroke prior to starting hemodialysis were excluded. Socio-demographic data, comorbidities, dialysis parameters, and data concerning the diagnosis of stroke were retrieved and analyzed.

Results

The dialysis vintage (duration of time on dialysis) averaged 11.4 ± 9.2 months. The incidence of stroke was 6.1 events per 1000 patient-years, with hemorrhagic stroke being most common (66%). Eighty percent of strokes occurred before the 30th month of dialysis. Sixty percent of strokes occurred within 24 h of a dialysis session. Predictive factors for stroke were diabetes mellitus (p = 0.026), heart failure (p = 0.045), poor dialysis compliance (p = 0.001), and short vintage (p = 0.001). The overall mortality rate was 52% and was higher for hemorrhagic stroke (60%). The leading causes of death were multiple organ failure and sepsis.

Conclusion

The incidence of stroke is high among hemodialysis patients in Cameroon and hemorrhagic stroke is the commonest type. Diabetes and heart failure triple the risk of stroke. Mortality in patients who suffered a stroke was high.

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喀麦隆维持性血液透析患者中的卒中及其相关性。

背景：终末期肾病是脑卒中的独立危险因素；然而，撒哈拉以南非洲的血液透析与中风之间的关系尚未确定。目的：评估喀麦隆维持性血液透析患者中风的发生率、相关因素和临床结果。方法：利用1060名维持性血液透患者（每周两次）的医疗档案数据，进行一项基于医院的回顾性研究。在开始血液透析之前患有中风的患者被排除在外。检索并分析了社会人口学数据、合并症、透析参数和与中风诊断有关的数据。结果：透析年份（透析持续时间）平均为11.4 ± 9.2 月。中风的发生率为每1000名患者年6.1次，其中出血性中风最为常见（66%）。80%的中风发生在透析的第30个月之前。60%的中风发生在24小时内 h透析。脑卒中的预测因素为糖尿病（p = 0.026）、心力衰竭（p = 0.045），透析依从性差（p = 0.001）和短年份（p = 0.001）。总死亡率为52%，出血性中风的死亡率更高（60%）。死亡的主要原因是多器官衰竭和败血症。结论：喀麦隆血液透析患者脑卒中发生率较高，出血性脑卒中是最常见的类型。糖尿病和心力衰竭是中风风险的三倍。中风患者的死亡率很高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Hemodialysis International UROLOGY & NEPHROLOGY-

CiteScore

2.50

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Hemodialysis International was originally an annual publication containing the Proceedings of the International Symposium on Hemodialysis held in conjunction with the Annual Dialysis Conference. Since 2003, Hemodialysis International is published quarterly and contains original papers on clinical and experimental topics related to dialysis in addition to the Annual Dialysis Conference supplement. This journal is a must-have for nephrologists, nurses, and technicians worldwide. Quarterly issues of Hemodialysis International are included with your membership to the International Society for Hemodialysis. The journal contains original articles, review articles, and commentary to keep readers completely updated in the field of hemodialysis. Edited by international and multidisciplinary experts, Hemodialysis International disseminates critical information in the field.