Pedro L Valenzuela, Aaron Baggish, Adrián Castillo-García, Alejandro Santos-Lozano, Araceli Boraita, Alejandro Lucia
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Abstract
Although the benefits of regular physical activity on cardiovascular health are well established, the effects of strenuous endurance exercise (SEE) have been a matter of debate since ancient times. In this article, we aim to provide a balanced overview of what is known about SEE and the heart-from epidemiological evidence to recent cardiac imaging findings. Lifelong SEE is overall cardioprotective, with endurance master athletes showing in fact a youthful heart. Yet, some lines of research remain open, such as the need to elucidate the time-course and potential relevance of transient declines in heart function (or increases in biomarkers of cardiac injury) with SEE. The underlying mechanisms and clinical relevance of SEE-associated atrial fibrillation, myocardial fibrosis, or high coronary artery calcium scores also remain to be elucidated. © 2022 American Physiological Society. Compr Physiol 12:1-19, 2022.
剧烈耐力运动与心脏:生理与病理适应。
尽管有规律的体育活动对心血管健康的好处是公认的，但自古以来，剧烈耐力运动(SEE)的影响一直是一个有争议的问题。在这篇文章中，我们旨在从流行病学证据到最近的心脏成像发现，对SEE和心脏的已知情况提供一个平衡的概述。终生的SEE对心脏有全面的保护作用，耐力高的运动员实际上表现出年轻的心脏。然而，一些研究领域仍然开放，例如需要阐明心脏功能的短暂下降(或心脏损伤生物标志物的增加)与SEE的时间过程和潜在相关性。see相关心房颤动、心肌纤维化或高冠状动脉钙评分的潜在机制和临床相关性也有待阐明。©2022美国生理学会。物理学报(英文版)，2012。
本文章由计算机程序翻译，如有差异，请以英文原文为准。
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