Termination of pregnancy in lupus nephritis: A bioethical analysis with the integrative method

Reumatologia clinica Pub Date : 2024-01-01 DOI:10.1016/j.reumae.2023.07.001

Tábata Cano-Gámez , Adriana Concepción Lobato-Belmonte , Ingris Peláez-Ballestas , Gabriel Medrano-Ramírez , Juan Carlos de León-Carbajal , Amaranta Manrique de Lara

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Abstract

Background and objective

Termination of pregnancy in patients with rheumatic diseases is controversial and a bioethical analysis is rarely performed. In this study we analysed the case of a pregnant patient with lupus nephritis unresponsive to treatment, for whom termination of pregnancy is considered.

Methods

The integrative model was applied combining different normative ethical theories.

Results

From a utilitarian perspective, termination of pregnancy is justifiable, seeking the greatest benefit for the greatest number of stakeholders. Deontology justifies both terminating and continuing the pregnancy, focusing on the action itself and on autonomy. In virtue ethics the importance of decisions rests with the person who performs the action seeking flourishing; termination of pregnancy would be justifiable.

Discussion and conclusions

Interruption of pregnancy is a justifiable solution following the integrative model. Bioethical analysis of paradigmatic cases is essential to ensure the best possible action and as a precedent for future similar situations in rheumatology.

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狼疮性肾炎患者终止妊娠：用综合方法进行生命伦理分析

背景和目的风湿病患者终止妊娠是一个有争议的问题，很少进行生物伦理分析。在本研究中，我们分析了一名对治疗无反应的狼疮性肾炎孕妇的病例，并考虑终止妊娠。方法采用综合模式，将不同的规范性伦理理论结合起来。道义论认为终止妊娠和继续妊娠都是合理的，重点在于行为本身和自主性。在美德伦理学中，决定的重要性在于采取行动的人是否追求幸福；终止妊娠是合理的。讨论与结论根据综合模式，终止妊娠是一种合理的解决方案。对典型病例进行生命伦理学分析对于确保采取最佳行动至关重要，同时也为今后风湿病学领域的类似情况开创了先例。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Reumatologia clinica

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