Postoperative surgical complications after pediatric kidney transplantation in low weight recipients (<15 kg): a systematic review.

IF 1.8 4区医学 Q3 TRANSPLANTATION

Current Opinion in Organ Transplantation Pub Date : 2023-08-01 Epub Date: 2023-05-19 DOI:10.1097/MOT.0000000000001074

Thomas Prudhomme, Benoit Mesnard, Olivier Abbo, Beatriz Banuelos, Angelo Territo

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引用次数: 0

Abstract

Purpose of review: Kidney transplantation in low-weight recipients (<15 kg) is a challenging surgery with special characteristics. We proposed to perform a systematic review to determine the postoperative complication rate and the type of complications after kidney transplantation in low-weight recipients (<15 kg). The secondary objectives were to determine graft survival, functional outcomes, and patient survival after kidney transplantation in low-weight recipients.

Methods: A systematic review was performed according to preferred reporting items for systematic reviews and meta-analyses. Medline and Embase databases were searched to identify all studies reporting outcomes on kidney transplantation in low-weight recipients (<15 kg).

Results: A total of 1254 patients in 23 studies were included. The median postoperative complications rate was 20.0%, while 87.5% of those were major complications (Clavien ≥3). Further, urological and vascular complications rates were 6.3% (2.0-11.9) and 5.0% (3.0-10.0), whereas the rate of venous thrombosis ranged from 0 to 5.6%. Median 10-year graft and patient survival were 76 and 91.0%.

Summary: Kidney transplantation in low-weight recipients is a challenging procedure complicated by a high rate of morbidity. Finally, pediatric kidney transplantation should be performed in centers with expertise and multidisciplinary pediatric teams.

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小儿肾移植术后低体重受者（<15 千克）的手术并发症：系统综述。

综述目的：低体重受者的肾移植（方法：根据系统综述和荟萃分析的首选报告项目进行系统综述。对 Medline 和 Embase 数据库进行了检索，以确定所有报告低体重受者肾移植结果的研究（结果：共纳入了 23 项研究中的 1254 名患者。术后并发症发生率中位数为 20.0%，其中 87.5% 为主要并发症（Clavien ≥3）。此外，泌尿系统和血管并发症的发生率分别为6.3%（2.0-11.9）和5.0%（3.0-10.0），而静脉血栓的发生率为0-5.6%。中位 10 年移植物存活率和患者存活率分别为 76% 和 91.0%。最后，小儿肾移植应在具备专业知识和多学科儿科团队的中心进行。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Opinion in Organ Transplantation 医学-移植

CiteScore

4.10

自引率

4.50%

发文量

124

审稿时长

6-12 weeks

期刊介绍： Current Opinion in Organ Transplantation is an indispensable resource featuring key, up-to-date and important advances in the field from around the world. Led by renowned guest editors for each section, every bimonthly issue of Current Opinion in Organ Transplantation delivers a fresh insight into topics such as stem cell transplantation, immunosuppression, tolerance induction and organ preservation and procurement. With 18 sections in total, the journal provides a convenient and thorough review of the field and will be of interest to researchers, surgeons and other healthcare professionals alike.