Prophylactic therapy for prevention of surgical site infection after extraction of third molar: An overview of reviews.

IF 2.2 3区医学

Medicina oral, patologia oral y cirugia bucal Pub Date : 2023-11-01 DOI:10.4317/medoral.25999

Y Cao, Q Jiang, J Hu

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引用次数: 0

Abstract

Background: To compare the effect of different prophylactic therapies on prevention of surgical site infection after extraction of third molars with different degree of impaction.

Material and methods: Systematic reviews and meta-analyses evaluating the effect of different prophylactic therapies on prevention of surgical site infection after extraction of third molars were included. An electronic search was performed in PubMed, EMBASE, and the Cochrane Database of Systematic reviews. AMSTAR 2 tool was used to evaluate the confidence in results from the included reviews. Descriptive analyses were performed.

Results: Six reviews were included. A significant benefit of different antibiotics to the prevention of site infection after extraction of third molars was reported. Amoxicillin/amoxicillin clavulanic acid could significantly reduce the rate of surgical site infection versus placebo. Chlorhexidine gel could significantly reduce the frequency of alveolar osteitis versus placebo.

Conclusions: Based on the limited evidence, there is a significant benefit of prophylactic therapy while the comparative effect of different types of prophylactic regimes are controversial.

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预防第三磨牙拔除后手术部位感染的预防性治疗：综述。

背景：比较不同预防性治疗方法对不同嵌顿程度第三磨牙拔除术后手术部位感染的预防效果。材料和方法：包括系统综述和荟萃分析，评估不同预防性治疗对第三磨牙拔除后手术部位感染的预防效果。在PubMed、EMBASE和Cochrane系统评价数据库中进行了电子搜索。AMSTAR 2工具用于评估纳入评审结果的置信度。进行描述性分析。结果：纳入6篇综述。报道了不同抗生素对预防第三磨牙拔除后局部感染的显著益处。与安慰剂相比，阿莫西林/阿莫西林-克拉维酸可显著降低手术部位感染率。与安慰剂相比，氯己定凝胶可以显著降低牙槽骨炎的发生率。结论：基于有限的证据，预防性治疗有显著的益处，而不同类型的预防方案的比较效果存在争议。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Medicina oral, patologia oral y cirugia bucal Medicine-Surgery

CiteScore

4.50

自引率

0.00%

发文量

期刊介绍： 1. Oral Medicine and Pathology: Clinicopathological as well as medical or surgical management aspects of diseases affecting oral mucosa, salivary glands, maxillary bones, as well as orofacial neurological disorders, and systemic conditions with an impact on the oral cavity. 2. Oral Surgery: Surgical management aspects of diseases affecting oral mucosa, salivary glands, maxillary bones, teeth, implants, oral surgical procedures. Surgical management of diseases affecting head and neck areas. 3. Medically compromised patients in Dentistry: Articles discussing medical problems in Odontology will also be included, with a special focus on the clinico-odontological management of medically compromised patients, and considerations regarding high-risk or disabled patients. 4. Implantology 5. Periodontology