Combined aerobic and resistance exercise in maintenance hemodialysis patients: A meta-analysis.

IF 1.4 4区 医学 Q3 UROLOGY & NEPHROLOGY
Seminars in Dialysis Pub Date : 2023-07-01 Epub Date: 2023-06-14 DOI:10.1111/sdi.13162
Yixiu Liu, Xiju Luo, Siyan Deng, Jing Chen, Lu Zhang, Ying Huang, Huagang Hu
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引用次数: 0

Abstract

Exercise brings many benefits to patients undergoing maintenance hemodialysis (MHD), but the effect of combined aerobic and resistance exercise remains unclear. English and Chinese databases (PubMed, Cochrane Library, Embase, Web of Science, CNKI, VIP, Wan Fang, and CBM) were searched from inception to January 2023 to retrieve qualified randomized controlled trials. The literature selection, data extraction, and risk of bias assessment of included studies were conducted independently by two reviewers. Meta-analysis was performed using RevMan 5.3 software. A total of 23 studies with 1214 participants were included, and 17 of the interventions were conducted during dialysis. Results showed that combined aerobic and resistance exercise (CARE) improved the peak oxygen uptake, six-minute walking test, 60 s sit-to-stand test (STS), 30 s STS, dialysis adequacy, five (out of eight) domains and physical component summary of health-related quality of life (HRQOL) measured by the Medical Outcomes Study Short Form-36, blood pressure, and hemoglobin for MHD patients compared with usual care. No significant changes were found in the mental component summary of HRQOL, C-reactive protein, creatinine, potassium, sodium, calcium, and phosphate. Subgroup analysis showed that intradialytic CARE ameliorated more outcomes, except for handgrip strength and hemoglobin, than non-intradialytic ones. CARE is an effective way to improve physical function, aerobic capacity, dialysis adequacy, and HRQOL for MHD patients. Strategies should be implemented by clinicians and policymakers to motivate patients to do more exercise. Well-designed clinical trials are warranted to explore the effectiveness of non-intradialytic CARE.

维持性血液透析患者的有氧和阻力联合运动:一项荟萃分析。
运动给接受维持性血液透析(MHD)的患者带来了许多好处,但有氧运动和阻力运动的联合效果尚不清楚。从开始到2023年1月,检索英文和中文数据库(PubMed、Cochrane Library、Embase、Web of Science、CNKI、VIP、Wan Fang和CBM),检索合格的随机对照试验。纳入研究的文献选择、数据提取和偏倚风险评估由两名评审员独立进行。使用RevMan 5.3软件进行荟萃分析。共纳入23项研究,共有1214名参与者,其中17项干预措施是在透析期间进行的。结果表明,有氧和阻力运动(CARE)相结合可以提高峰值摄氧量、6分钟步行测试、60 s坐立式测试(STS),30 与常规护理相比,MHD患者的STS、透析充分性、五个(八个)领域和健康相关生活质量(HRQOL)的物理成分总结(通过医疗结果研究简表36测量)、血压和血红蛋白。HRQOL、C反应蛋白、肌酸酐、钾、钠、钙和磷酸盐的心理成分汇总没有发现显著变化。亚组分析显示,除握力和血红蛋白外,透析内CARE比非透析外改善了更多的结果。CARE是改善MHD患者身体功能、有氧能力、透析充分性和HRQOL的有效方法。临床医生和决策者应该实施策略,激励患者进行更多的锻炼。精心设计的临床试验有助于探索非透析CARE的有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Seminars in Dialysis
Seminars in Dialysis 医学-泌尿学与肾脏学
CiteScore
3.00
自引率
6.20%
发文量
91
审稿时长
4-8 weeks
期刊介绍: Seminars in Dialysis is a bimonthly publication focusing exclusively on cutting-edge clinical aspects of dialysis therapy. Besides publishing papers by the most respected names in the field of dialysis, the Journal has unique useful features, all designed to keep you current: -Fellows Forum -Dialysis rounds -Editorials -Opinions -Briefly noted -Summary and Comment -Guest Edited Issues -Special Articles Virtually everything you read in Seminars in Dialysis is written or solicited by the editors after choosing the most effective of nine different editorial styles and formats. They know that facts, speculations, ''how-to-do-it'' information, opinions, and news reports all play important roles in your education and the patient care you provide. Alternate issues of the journal are guest edited and focus on a single clinical topic in dialysis.
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