Zubair Hasan, Michael Lee, Fiona Chen, Seraphina Key, Al-Rahim Habib, Layal Aweidah, Raymond Sacks, Narinder Singh
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引用次数: 0
Abstract
Background: Pneumatization of the mastoid process is variable and of significance to the operative surgeon. Surgical approaches to the temporal bone require an understanding of pneumatization and its implications for surgical access. This study aims to determine the feasibility of using deep learning convolutional neural network algorithms to classify pneumatization of the mastoid process.
Methods: De-identified petrous temporal bone images were acquired from a tertiary hospital radiology picture archiving and communication system. A binary classification mode in the pretrained convolutional neural network was used to investigate the utility of convolutional neural networks in temporal bone imaging. False positive and negative images were reanalyzed by the investigators and qualitatively assessed to consider reasons for inaccuracy.
Results: The overall accuracy of the model was 0.954. At a probability threshold of 65%, the sensitivity of the model was 0.860 (95% CI 0.783-0.934) and the specificity was 0.989 (95% CI 0.960-0.999). The positive predictive value was 0.973 (95% CI 0.904-0.993) and the negative predictive value was 0.935 (95% CI 0.901-0.965). The false positive rate was 0.006. The F1 number was 0.926 demonstrating a high accuracy for the model.
Conclusion: The temporal bone is a complex anatomical region of interest to otolaryngologists. Surgical planning requires high-resolution computed tomography scans, the interpretation of which can be augmented with machine learning. This initial study demonstrates the feasibility of utilizing machine learning algorithms to discriminate anatomical variation with a high degree of accuracy. It is hoped this will lead to further investigation regarding more complex anatomical structures in the temporal bone.
背景:乳突气化是可变的,对外科医生有重要意义。颞骨的手术入路需要了解气动及其对手术入路的影响。本研究旨在确定使用深度学习卷积神经网络算法对乳突气化进行分类的可行性。方法:从某三级医院放射影像档案及通讯系统中获取去识别的颞骨岩质图像。采用预训练卷积神经网络中的二值分类模式,研究了卷积神经网络在颞骨成像中的应用。假阳性和阴性图像由调查人员重新分析和定性评估,以考虑不准确的原因。结果:模型的总体准确度为0.954。在65%的概率阈值下,模型的敏感性为0.860 (95% CI 0.783-0.934),特异性为0.989 (95% CI 0.960-0.999)。阳性预测值为0.973 (95% CI 0.904 ~ 0.993),阴性预测值为0.935 (95% CI 0.901 ~ 0.965)。假阳性率为0.006。F1值为0.926,表明模型具有较高的精度。结论:颞骨是耳鼻喉科医师感兴趣的复杂解剖区域。手术计划需要高分辨率的计算机断层扫描,机器学习可以增强对其的解释。这项初步研究证明了利用机器学习算法以高精度区分解剖变异的可行性。希望这将导致对颞骨更复杂解剖结构的进一步研究。
期刊介绍:
The Journal of International Advanced Otology (IAO – Citation Abbreviation: J Int Adv Otol) is an open access double-blind peer-reviewed, international publication. The Journal of International Advanced Otology is fully sponsored and owned by the European Academy of Otology and Neurotology and the Politzer Society. The Journal of International Advanced Otology is published 3 times per year on April, August, December and its publication language is English.
The scope of the Journal is limited with otology, neurotology, audiology (excluding linguistics) and skull base medicine.
The Journal of International Advanced Otology aims to publish manuscripts at the highest clinical and scientific level. IAO publishes original articles in the form of clinical and basic research, review articles, short reports and a limited number of case reports. Controversial patient discussions, communications on emerging technology, and historical issues will also be considered for publication.