Severe autoimune thyreotoxicosis complicated by febrile neutropenia as a result of thyreostatic therapy.

Q4 Medicine
Marie Jarolímová, Michal Kazmíř
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引用次数: 0

Abstract

Hyperthyreoidism is a clinical manifestation of excessive production of thyroid hormones. In most cases pacient ´s condition allows ambulant treatment. Rarely, it can develop into an acute, life- threatening thyrotoxic crisis which has to be treated in the intensive care unit. Main therapy includes antithyroid medication, corticosteroids, beta- blockers and rehydratation, mostly parenteral. If initial treatment fails, plasmapheresis provides effective strategy. Antithyroid medication may come with side effects as rash, digestive issues, joint pain.Agranulocystosis or acute liver lesion which leads to liver failure belong among the most severe ones. In this case we report a pacient with thyrotoxic crisis, atrial fibrilation which led to ventricular fibrilation, cor thyreotoxicum. The treatment was complicated by febrile neutropenia.

严重的自身免疫性甲状腺毒症并发发热性中性粒细胞减少症,这是甲状腺激素治疗的结果。
甲状腺功能亢进症是甲状腺激素分泌过多的一种临床表现。在大多数情况下,患者的病情允许在救护车上接受治疗。极少数情况下,它会发展成急性、危及生命的甲亢危象,必须在重症监护室进行治疗。主要治疗方法包括抗甲状腺药物、皮质类固醇、β-受体阻滞剂和补液(大多为肠外补液)。如果初始治疗失败,血浆置换也是一种有效的策略。抗甲状腺药物可能会产生皮疹、消化问题、关节疼痛等副作用。粒细胞囊肿病或急性肝脏病变会导致肝功能衰竭,属于最严重的疾病。在本病例中,我们报告了一名患有甲亢危象、心房颤动导致心室颤动、甲状腺毒血症的患者。发热性中性粒细胞减少症使治疗变得复杂。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Vnitrni lekarstvi
Vnitrni lekarstvi Medicine-Internal Medicine
CiteScore
0.50
自引率
0.00%
发文量
104
期刊介绍: Vnitřní lékařství je tiskovým orgánem České internistické společnosti České lékařské společnosti Jana Evangelisty Purkyně a Slovenskej internistickej spoločnosti Slovenskej lekárskej spoločnosti. Je vydáván nepřetržitě od roku 1955. Časopis vychází jako měsíčník, tedy 12krát do roka a podle potřeby jsou v běžném ročníku vydávána jeho suplementa, která jsou obsahově zaměřena k určitému tématu. Tematicky je časopis zaměřen široce na oblast interní medicíny se zvláštní pozorností ke kardiologii, diabetologii a poruchám metabolizmu.
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