Evaluating the benefits of a second pain treatment following a clinical trial.

IF 1.9 4区医学 Q3 PSYCHOLOGY, CLINICAL

Rehabilitation Psychology Pub Date : 2024-02-01 Epub Date: 2023-06-19 DOI:10.1037/rep0000510

Tracy M Anastas, Aaron P Turner, Erica J Ho, Melissa A Day, Dawn M Ehde, Mark P Jensen, Rhonda M Williams

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引用次数: 0

Abstract

Objective: To examine the value of including an open label phase after a clinical trial of pain treatments by examining participant characteristics and potential benefits.

Method: Secondary data analysis. Veterans with chronic pain who completed a randomized controlled trial (RCT) comparing hypnosis, mindfulness meditation, and pain education were invited to participate in an open label phase. Average and worst pain intensities, pain interference, and depression were assessed pre- and postopen label phase; global impressions of change and treatment satisfaction were assessed at postopen label phase only.

Results: Of those who were offered the open label phase, 40% (n = 68) enrolled. Enrollees were likely to be older, to have attended more sessions in the RCT, to be satisfied with their first treatment, and to perceive improvement in their ability to manage pain after the RCT. In the open label phase, depression and worst pain decreased across all three treatment conditions. No other improvements were observed. However, most Veterans perceived improvements in pain intensity, ability to manage pain, and pain interference, and were satisfied with the second intervention.

Conclusions: There appears to be some value to adding an open label phase to the end of a trial of pain treatments. A substantial portion of study participants elected to participate and reported it to be beneficial. Exploring data from an open label phase can illuminate important aspects of patient experience, barriers to and facilitators of care, as well as treatment preferences. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

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评估临床试验后第二次疼痛治疗的益处。

目的通过研究参与者的特征和潜在益处，探讨在疼痛治疗临床试验后加入开放标签阶段的价值：方法：二次数据分析。曾完成随机对照试验（RCT）、比较催眠、正念冥想和疼痛教育的慢性疼痛退伍军人受邀参加开放标签阶段。对开放标签阶段前后的平均和最严重疼痛强度、疼痛干扰和抑郁情况进行了评估；仅在开放标签阶段后对总体变化印象和治疗满意度进行了评估：在接受开放标签阶段治疗的患者中，40%（68 人）参加了治疗。参加者的年龄可能较大，参加的治疗次数可能较多，对首次治疗感到满意，并认为治疗后控制疼痛的能力有所提高。在开放标签阶段，抑郁和最严重的疼痛在所有三种治疗条件下都有所减轻。没有观察到其他改善。不过，大多数退伍军人认为疼痛强度、控制疼痛的能力和疼痛干扰有所改善，并对第二次干预表示满意：结论：在疼痛治疗试验的最后增加一个开放标签阶段似乎有一定的价值。相当一部分研究参与者选择参与其中，并报告说这是有益的。探索开放标签阶段的数据可以揭示患者体验、护理障碍和促进因素以及治疗偏好等重要方面。(PsycInfo Database Record (c) 2023 APA，保留所有权利）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Rehabilitation Psychology Multiple-

CiteScore

4.80

自引率

7.40%

发文量

期刊介绍： Rehabilitation Psychology is a quarterly peer-reviewed journal that publishes articles in furtherance of the mission of Division 22 (Rehabilitation Psychology) of the American Psychological Association and to advance the science and practice of rehabilitation psychology. Rehabilitation psychologists consider the entire network of biological, psychological, social, environmental, and political factors that affect the functioning of persons with disabilities or chronic illness. Given the breadth of rehabilitation psychology, the journal"s scope is broadly defined.