Ageing and the Autonomic Nervous System.

Q1 Biochemistry, Genetics and Molecular Biology

Sub-cellular biochemistry Pub Date : 2023-01-01 DOI:10.1007/978-3-031-26576-1_10

Michael Takla, Khalil Saadeh, Gary Tse, Christopher L-H Huang, Kamalan Jeevaratnam

引用次数: 1

Abstract

The vertebrate nervous system is divided into central (CNS) and peripheral (PNS) components. In turn, the PNS is divided into the autonomic (ANS) and enteric (ENS) nervous systems. Ageing implicates time-related changes to anatomy and physiology in reducing organismal fitness. In the case of the CNS, there exists substantial experimental evidence of the effects of age on individual neuronal and glial function. Although many such changes have yet to be experimentally observed in the PNS, there is considerable evidence of the role of ageing in the decline of ANS function over time. As such, this chapter will argue that the ANS constitutes a paradigm for the physiological consequences of ageing, as well as for their clinical implications.

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衰老和自主神经系统。

脊椎动物的神经系统分为中枢(CNS)和外周(PNS)两部分。PNS又分为自主神经系统(ANS)和肠神经系统(ENS)。衰老涉及与时间相关的解剖学和生理学变化，从而降低了机体的适应性。就中枢神经系统而言，有大量的实验证据表明年龄对单个神经元和神经胶质功能的影响。虽然许多这样的变化尚未在PNS实验中观察到，但有相当多的证据表明，随着时间的推移，衰老在ANS功能下降中的作用。因此，本章将论证ANS构成了衰老生理后果的范例，以及它们的临床意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Sub-cellular biochemistry Biochemistry, Genetics and Molecular Biology-Biochemistry

CiteScore

5.90

自引率

0.00%

发文量

期刊介绍： The book series SUBCELLULAR BIOCHEMISTRY is a renowned and well recognized forum for disseminating advances of emerging topics in Cell Biology and related subjects. All volumes are edited by established scientists and the individual chapters are written by experts on the relevant topic. The individual chapters of each volume are fully citable and indexed in Medline/Pubmed to ensure maximum visibility of the work.