Infectious diseases and social distancing under state-dependent probabilities

IF 4.4 3区 管理学 Q1 OPERATIONS RESEARCH & MANAGEMENT SCIENCE
Davide La Torre, Simone Marsiglio, Fabio Privileggi
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Abstract

We analyze the implications of infectious diseases and social distancing in an extended SIS framework to allow for the presence of stochastic shocks with state dependent probabilities. Random shocks give rise to the diffusion of a new strain of the disease which affects both the number of infectives and the average biological characteristics of the pathogen causing the disease. The probability of such shock realizations changes with the level of disease prevalence and we analyze how the properties of the state-dependent probability function affect the long run epidemiological outcome which is characterized by an invariant probability distribution supported on a range of positive prevalence levels. We show that social distancing reduces the size of the support of the steady state distribution decreasing thus the variability of disease prevalence, but in so doing it also shifts the support rightward allowing eventually for more infectives than in an uncontrolled framework. Nevertheless, social distancing is an effective control measure since it concentrates most of the mass of the distribution toward the lower extreme of its support.

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国家相关概率下的传染病和社交距离。
我们在一个扩展的SIS框架中分析了传染病和社交距离的影响,以允许存在具有状态相关概率的随机冲击。随机冲击会导致一种新的疾病株的传播,这会影响感染者的数量和致病病原体的平均生物学特征。这种休克实现的概率随着疾病流行水平的变化而变化,我们分析了状态相关概率函数的性质如何影响长期流行病学结果,其特征是在一系列阳性流行水平上支持不变的概率分布。我们表明,保持社交距离会减少对稳态分布的支持,从而降低疾病流行率的可变性,但这样做也会将支持向右转移,最终导致比不受控制的框架中更多的传染性。尽管如此,保持社交距离是一种有效的控制措施,因为它将大部分分配集中在其支持的下限。
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来源期刊
Annals of Operations Research
Annals of Operations Research 管理科学-运筹学与管理科学
CiteScore
7.90
自引率
16.70%
发文量
596
审稿时长
8.4 months
期刊介绍: The Annals of Operations Research publishes peer-reviewed original articles dealing with key aspects of operations research, including theory, practice, and computation. The journal publishes full-length research articles, short notes, expositions and surveys, reports on computational studies, and case studies that present new and innovative practical applications. In addition to regular issues, the journal publishes periodic special volumes that focus on defined fields of operations research, ranging from the highly theoretical to the algorithmic and the applied. These volumes have one or more Guest Editors who are responsible for collecting the papers and overseeing the refereeing process.
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