{"title":"xTMS: A Pulse Generator for Exploring Transcranial Magnetic Stimulation Therapies.","authors":"Kawsar Ali, Karen Wendt, Majid Memarian Sorkhabi, Moaad Benjaber, Timothy Denison, Daniel J Rogers","doi":"10.1109/APEC43580.2023.10131554","DOIUrl":null,"url":null,"abstract":"<p><p>A cascaded H-bridge based pulse generator for transcranial magnetic stimulation is introduced. The system demonstrates complete flexibility for producing different shape, duration, direction, and rate of repetition of stimulus pulses within its electrical limits, and can emulate all commercial and research systems available to-date in this application space. An offline model predictive control algorithm, used to generate pulses and sequences, shows superior performance compared to conventional carrier-based pulse width modulation. A fully functioning laboratory prototype delivers up to 1.5 kV, 6 kA pulses, and is ready to be used as a research tool for the exploration of transcranial magnetic stimulation therapies by leveraging the many degrees-of-freedom offered by the design.</p>","PeriodicalId":72690,"journal":{"name":"Conference proceedings. IEEE Applied Power Electronics Conference and Exposition","volume":"2023 ","pages":"1875-1880"},"PeriodicalIF":0.0000,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614672/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Conference proceedings. IEEE Applied Power Electronics Conference and Exposition","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/APEC43580.2023.10131554","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A cascaded H-bridge based pulse generator for transcranial magnetic stimulation is introduced. The system demonstrates complete flexibility for producing different shape, duration, direction, and rate of repetition of stimulus pulses within its electrical limits, and can emulate all commercial and research systems available to-date in this application space. An offline model predictive control algorithm, used to generate pulses and sequences, shows superior performance compared to conventional carrier-based pulse width modulation. A fully functioning laboratory prototype delivers up to 1.5 kV, 6 kA pulses, and is ready to be used as a research tool for the exploration of transcranial magnetic stimulation therapies by leveraging the many degrees-of-freedom offered by the design.
本文介绍了一种基于级联 H 桥的经颅磁刺激脉冲发生器。该系统具有完全的灵活性，可在其电气限制范围内产生不同形状、持续时间、方向和重复率的刺激脉冲，并可模拟该应用领域迄今可用的所有商业和研究系统。用于产生脉冲和序列的离线模型预测控制算法与传统的基于载波的脉宽调制相比，显示出卓越的性能。功能齐全的实验室原型可提供高达 1.5 kV、6 kA 的脉冲，并可作为研究工具，利用设计提供的多种自由度探索经颅磁刺激疗法。
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