Association Between Overweight/Obesity and ART Drug Regimen Among Adult HIV Patients in Gamo Zone Public Health Facilities Southern Ethiopia.

IF 1.5 Q4 INFECTIOUS DISEASES
HIV AIDS-Research and Palliative Care Pub Date : 2023-06-15 eCollection Date: 2023-01-01 DOI:10.2147/HIV.S412586
Nigus Kabtu Belete, Darik Temesgen Assefa, Tesfaye Feleke Gadore, Manaye Yihune Teshale, Eshetu Zerihun Tariku
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引用次数: 0

Abstract

Introduction: Overweight/obesity is an emerging public health problem in low income countries. Currently sub-Saharan African countries are facing a double burden of malnutrition. Evidence has shown that overweight/obesity is becoming a problem for people living with HIV. But little is known in our setting. Thus, this study is designed to assess the association between overweight/obesity and ART drug regimen among adult HIV patients in Gamo zone public health facilities southern Ethiopia.

Objective: To assess the association between overweight/obesity and ART drug regimen among adult HIV patients in Gamo zone public health facilities southern Ethiopia.

Methods: Institution-based cross-sectional study was conducted from April 10 to May 10, 2022, among systematically selected adult HIV patients. The data were collected by using a structured interviewer-administered questionnaire, patient record review, and physical measurements. Multivariate logistic regression model was used to assess the association between dependent and independent variables. A p-value <0.05 with its 95% CI was considered as a statistically significant and interpreted accordingly.

Results: The magnitude of overweight/obesity were 13.5% (95% CI:(10.4-17.2)). Being male (2.484(1.308, 4.716)), duration on ART (took for ≥5 years) ((2.249(1.218, 4.152)), and ART drug regime (3.789(1.965, 7.304)) were significantly associated with overweight/obesity.

Conclusion: Overweight/obesity is significantly associated to ART drug regimen type among adult HIV patients. Furthermore, sex and duration on ART drug were found significantly associated with overweight/obesity of adult HIV patients.

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埃塞俄比亚南部加莫地区公共卫生机构成年艾滋病毒患者超重/肥胖与抗逆转录病毒药物方案的关系。
引言:超重/肥胖是低收入国家新出现的公共卫生问题。目前,撒哈拉以南非洲国家正面临营养不良的双重负担。有证据表明,超重/肥胖正在成为艾滋病毒感染者的一个问题。但在我们的环境中却鲜为人知。因此本研究旨在评估埃塞俄比亚南部加莫地区公共卫生设施中成年艾滋病毒患者的超重/肥胖与抗逆转录病毒治疗药物方案之间的关系于2022年4月10日至5月10日在系统选择的成年HIV患者中进行。通过使用结构化访谈者管理的问卷、患者记录回顾和身体测量来收集数据。多变量逻辑回归模型用于评估因变量和自变量之间的相关性。结果:超重/肥胖的程度为13.5%(95%可信区间:(10.4-17.2))。男性(2.484(1.308,4.716))、抗逆转录病毒治疗持续时间(≥5年)(2.249(1.218,4.152))和抗逆转录病毒药物治疗方案(3.789(1.965,7.304))与超重/肥胖显著相关。此外,性别和抗逆转录病毒治疗药物的持续时间与成年HIV患者的超重/肥胖显著相关。
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来源期刊
CiteScore
3.00
自引率
6.70%
发文量
61
审稿时长
16 weeks
期刊介绍: About Dove Medical Press Dove Medical Press Ltd is part of Taylor & Francis Group, the Academic Publishing Division of Informa PLC. We specialize in the publication of Open Access peer-reviewed journals across the broad spectrum of science, technology and especially medicine. Dove Medical Press was founded in 2003 with the objective of combining the highest editorial standards with the ''best of breed'' new publishing technologies. We have offices in Manchester and London in the United Kingdom, representatives in Princeton, New Jersey in the United States, and our editorial offices are in Auckland, New Zealand. Dr Scott Fraser is our Medical Director based in the UK. He has been in full time clinical practice for over 20 years as well as having an active research interest.
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