Improved extremity tissue oxygenation with short-term exposure to textiles embedded with far infrared light emitting thermoactive particles in patients with diabetes mellitus.

IF 2.8 4区医学 Q3 ENDOCRINOLOGY & METABOLISM

Diabetes & Vascular Disease Research Pub Date : 2023-03-01 DOI:10.1177/14791641231170282

Diana Athonvarangkul, Kaicheng Wang, Yanhong Deng, Silvio E Inzucchi, Adam Mayerson

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引用次数: 0

Abstract

Methods: A single-center, prospective, randomized, placebo-controlled, double-blinded, crossover study of 32 subjects with either type 1 or type 2 DM. An active FIR wrap followed by a placebo wrap (or vice versa) was applied to the arm, calf, ankle, and forefoot for 60 min each with continuous TcPO₂ measurements. The treatment effect of the active versus placebo wrap was estimated using a linear mixed effect model adjusted for period, sequence, baseline value, and anatomic site.

Results: The active FIR wrap increased mean TcPO₂ at the arm (2.6 ± 0.8 mmHg, p = .002), calf (1.5 ± 0.7 mmHg, p = .03), and ankle (1.7 ± 0.8 mmHg, p = .04) and composite of all sites (1.4 ± 0.5 mmHg, p = .002) after 60 min. The estimated treatment effect was significant for the active FIR wrap at the calf (1.5 ± 0.7 mmHg, p = .045) and in composite of all sites (1.2 ± 0.5 mmHg, p = .013).

Conclusion: Short-term exposure to FIR textiles improves peripheral tissue oxygenation in patients with diabetes.

Abstract Image

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糖尿病患者短期接触嵌有远红外线热敏微粒的纺织品可改善肢体组织的氧合。

研究方法对 32 名 1 型或 2 型糖尿病患者进行单中心、前瞻性、随机、安慰剂对照、双盲、交叉研究。先在手臂、小腿、脚踝和前脚掌处使用活性 FIR 包裹，再使用安慰剂包裹（反之亦然），每次持续 60 分钟，并连续测量 TcPO2。采用线性混合效应模型估算了活性敷料与安慰剂敷料的治疗效果，并对时间段、顺序、基线值和解剖部位进行了调整：结果：60 分钟后，活性 FIR 包裹提高了手臂（2.6 ± 0.8 mmHg，p = .002）、小腿（1.5 ± 0.7 mmHg，p = .03）和脚踝（1.7 ± 0.8 mmHg，p = .04）的平均 TcPO2，并提高了所有部位的综合 TcPO2（1.4 ± 0.5 mmHg，p = .002）。对小腿处的活性 FIR 包裹（1.5 ± 0.7 mmHg，p = .045）和所有部位的综合（1.2 ± 0.5 mmHg，p = .013）的估计治疗效果显著：结论：短期接触发热织物可改善糖尿病患者的外周组织氧合。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diabetes & Vascular Disease Research ENDOCRINOLOGY & METABOLISM-PERIPHERAL VASCULAR DISEASE

CiteScore

4.40

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Diabetes & Vascular Disease Research is the first international peer-reviewed journal to unite diabetes and vascular disease in a single title. The journal publishes original papers, research letters and reviews. This journal is a member of the Committee on Publication Ethics (COPE)