Trabecular Bone Remodeling After Posterior Lumbar Interbody Fusion: Comparison of Three-Dimensional Porous Tantalum and Titanium-Coated Polyetheretherketone Interbody Cages.

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS

ACS Applied Bio Materials Pub Date : 2024-09-01 Epub Date: 2023-04-15 DOI:10.1177/21925682231170613

Naoki Segi, Hiroaki Nakashima, Ryuichi Shinjo, Yujiro Kagami, Masaaki Machino, Sadayuki Ito, Jun Ouchida, Kazuaki Morishita, Ryotaro Oishi, Ippei Yamauchi, Shiro Imagama

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引用次数: 0

Abstract

Study design: Retrospective cohort study.

Objectives: The criteria for determining completion of intervertebral stability after posterior lumbar interbody fusion (PLIF) remain controversial. Several new radiological indicators of bone growth and osteointegration have been established. We compared computed tomography (CT) findings related to osteointegration after PLIF with interbody cages of two different materials and designs.

Methods: We retrospectively analyzed data from 103 patients who underwent PLIF with three-dimensional porous tantalum (Tn) cages or titanium-coated polyetheretherketone (TiP) cages. CT images obtained 3 months and 1 year after surgery were examined for trabecular bone remodeling (TBR), cancellous condensation (CC), and vertebral endplate cyst (VEC) formation. The incidences of each finding were compared by cage type, and rates of instrument failure and pseudarthrosis were determined.

Results: Three months postoperatively, 87% of the levels with Tn cages exhibited TBR, whereas 96% of those with TiP cages did not (P < .001). Most levels with Tn cages levels exhibited TBR and no CC 3 months (81%) and 1 year (94%) after surgery. Although 78% of levels with TiP cages exhibited CC and no TBR 3 months after surgery, 59% exhibited both CC and TBR 1 year after surgery. Significantly fewer VECs formed around the Tn cages than around the TiP cages both 3 months (P = .002) and 1 year (P < .001) after surgery. Implant-related problems occurred at levels that exhibited neither TBR nor CC.

Conclusions: The porous tantalum cage may enable intervertebral stability that is comparable to bony fusion soon after surgery.

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后路腰椎椎体间融合术后的骨小梁重塑：三维多孔钽和钛涂层聚醚醚酮椎体间骨架的比较。

研究设计研究目的：回顾性队列研究：后路腰椎椎体间融合术（PLIF）后椎体间稳定性的判定标准仍存在争议。一些新的骨生长和骨整合放射学指标已经确立。我们比较了使用两种不同材料和设计的椎体间融合器进行 PLIF 后与骨整合相关的计算机断层扫描（CT）结果：我们回顾性分析了103名接受PLIF术的患者的数据，这些患者使用了三维多孔钽（Tn）椎体间架或钛涂层聚醚醚酮（TiP）椎体间架。对术后 3 个月和 1 年的 CT 图像进行了检查，以了解骨小梁重塑 (TBR)、松质骨凝结 (CC) 和椎体终板囊肿 (VEC) 的形成情况。结果显示：术后三个月，87%的椎体内板囊肿患者在术后一年内出现骨小梁重塑（TBR）、松质骨冷凝（CC）和椎体内板囊肿（VEC）：术后三个月，87%使用Tn保持架的椎体出现TBR，而96%使用TiP保持架的椎体没有TBR（P < .001）。术后 3 个月（81%）和 1 年（94%），大多数使用 Tn 笼的水平显示 TBR 且无 CC。虽然 78% 带有 TiP 笼的水平在术后 3 个月表现出 CC 而没有 TBR，但 59% 的水平在术后 1 年表现出 CC 和 TBR。术后 3 个月（P = .002）和 1 年（P < .001），在 Tn 骨架周围形成的 VEC 明显少于在 TiP 骨架周围形成的 VEC。与种植体相关的问题发生在既不显示 TBR 也不显示 CC 的水平：结论：多孔钽笼可在术后不久实现与骨性融合相当的椎间稳定性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Applied Bio Materials Chemistry-Chemistry (all)

CiteScore

9.40

自引率

2.10%

发文量

464