Consistency of left ventricular ejection fraction measurements in the early time course of STEMI.

IF 2.1 4区 医学 Q3 HEMATOLOGY
Lilyana Georgieva, Fabian T Nienhaus, Sebastian Haberkorn, Ralf Erkens, Amin Polzin, Patricia Wischmann, Rojda Ipek, Kian Marjani, Aikaterini Christidi, Michael Roden, Christian Jung, Florian Bönner, Malte Kelm, Stefan Perings, Mareike Gastl
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引用次数: 0

Abstract

Background: Early after ST-segment elevation myocardial infarction (STEMI), initial LV reshaping and hypokinesia may affect analysis of LV function. Concomitant microvascular dysfunction may affect LV function as well.

Objective: To perform a comparative evaluation of left ventricular ejection fraction (LVEF) and stroke volume (SV) by different imaging modalities to assess LV function early after STEMI.

Methods: LVEF and SV were assessed using serial imaging within 24 h and 5 days after STEMI using cineventriculography (CVG), 2-dimensional echocardiography (2DE), 2D/3D cardiovascular magnetic resonance (CMR) (2D/3D) in 82 patients.

Results: 2D analyses of LVEF using CVG, 2DE and 2D CMR yielded uniform results within 24 h and 5 days of STEMI. SV assessment between CVG and 2DE was comparable, whereas values for SV were higher using 2D CMR (p < 0.01 all). This was due to higher LVEDV measurements. LVEF by 2D versus 3D CMR was comparable, 3D CMR yielded higher volumetric values. This was not influenced by infarct location or infarct size.

Conclusions: 2D analysis of LVEF yielded robust results across all imaging techniques implying that CVG, 2DE, and 2D CMR can be used interchangeably early after STEMI. SV measurements differed substantially between imaging techniques due to higher intermodality-differences of absolute volumetric measurements.

STEMI早期左室射血分数测量的一致性。
背景:st段抬高型心肌梗死(STEMI)后早期,初始左室重塑和运动不足可能影响左室功能分析。伴随的微血管功能障碍也可能影响左室功能。目的:通过不同成像方式对STEMI患者左室射血分数(LVEF)和脑卒中容积(SV)进行比较评价,评价STEMI患者早期左室功能。方法:对82例STEMI后24 h和5 d内的LVEF和SV进行连续成像,分别采用电影心室造影(CVG)、二维超声心动图(2DE)、2D/3D心血管磁共振(CMR) (2D/3D)。结果:使用CVG、2DE和2D CMR对LVEF进行二维分析,在STEMI后24 h和5天内得到一致的结果。CVG和2DE之间的SV评估具有可比性,而2D CMR的SV值更高(p结论:LVEF的2D分析在所有成像技术中产生了强有力的结果,这意味着CVG、2DE和2D CMR可以在STEMI后早期互换使用。由于绝对体积测量的模态差异较大,不同成像技术之间的SV测量存在很大差异。
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来源期刊
CiteScore
4.30
自引率
33.30%
发文量
170
期刊介绍: Clinical Hemorheology and Microcirculation, a peer-reviewed international scientific journal, serves as an aid to understanding the flow properties of blood and the relationship to normal and abnormal physiology. The rapidly expanding science of hemorheology concerns blood, its components and the blood vessels with which blood interacts. It includes perihemorheology, i.e., the rheology of fluid and structures in the perivascular and interstitial spaces as well as the lymphatic system. The clinical aspects include pathogenesis, symptomatology and diagnostic methods, and the fields of prophylaxis and therapy in all branches of medicine and surgery, pharmacology and drug research. The endeavour of the Editors-in-Chief and publishers of Clinical Hemorheology and Microcirculation is to bring together contributions from those working in various fields related to blood flow all over the world. The editors of Clinical Hemorheology and Microcirculation are from those countries in Europe, Asia, Australia and America where appreciable work in clinical hemorheology and microcirculation is being carried out. Each editor takes responsibility to decide on the acceptance of a manuscript. He is required to have the manuscript appraised by two referees and may be one of them himself. The executive editorial office, to which the manuscripts have been submitted, is responsible for rapid handling of the reviewing process. Clinical Hemorheology and Microcirculation accepts original papers, brief communications, mini-reports and letters to the Editors-in-Chief. Review articles, providing general views and new insights into related subjects, are regularly invited by the Editors-in-Chief. Proceedings of international and national conferences on clinical hemorheology (in original form or as abstracts) complete the range of editorial features.
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