The Prevalence and Risk Factors of Electrical Status Epilepticus During Slow-Wave Sleep in Self-Limited Epilepsy With Centrotemporal Spikes.

IF 1.6 4区 医学 Q3 CLINICAL NEUROLOGY
Clinical EEG and Neuroscience Pub Date : 2024-03-01 Epub Date: 2023-06-18 DOI:10.1177/15500594231182758
Guangshuang Lu, Yun Cheng, Yun Wang, Jie Hu, Fan Zhang, Wenbo Li, Minnong Xia, Xiaoyan Lu, Wu Yang
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引用次数: 0

Abstract

Objective. To investigate the prevalence and risk factors for electrical status epilepticus during slow-wave sleep (ESES) in patients with self-limited epilepsy with centrotemporal spikes (SeLECTS). Methods. The clinical and follow-up data of children with SeLECTS were collected between 2017 and 2021. Patients were divided into typical ESES, atypical ESES, and non-ESES groups according to spike-wave indices (SWI). Clinical and electroencephalography characteristics were retrospectively analyzed. Logistic regression was used to identify risk factors for ESES. Results. A total of 95 patients with SeLECTS were enrolled. Seven patients (7.4%) developed typical ESES, 30 (31.6%) developed atypical ESES, 25 (26.3%) developed ESES at the first visit, and 12 (12.6%) developed ESES during treatment and follow-up. Multivariate logistic regression analysis showed that the risk factors for SeLECTS combined with ESES were Rolandic double or multiple spikes (OR = 8.626, 95% CI: 2.644-28.147, P < .001) and Rolandic slow waves (OR = 53.550, 95% CI: 6.339-452.368, P < .001). There were no significant differences in seizure characteristics, electroencephalogram (EEG) findings, or cognitive impairment between the atypical and typical ESES groups. Conclusion. More than one-third of the SeLECTS patients combined with ESES. Both atypical and typical ESES scores can affect cognitive function. On electroencephalography, interictal Rolandic double/multiple spikes and slow-wave abnormalities may indicate SeLECTS with ESES.

伴有中心颞区棘波的自限性癫痫患者慢波睡眠时电癫痫状态的发生率和风险因素
研究目的调查自限性癫痫伴颞叶中心棘波(SeLECTS)患者在慢波睡眠中电癫痫状态(ESES)的发生率和风险因素。研究方法收集了2017年至2021年间SeLECTS患儿的临床和随访数据。根据尖波指数(SWI)将患者分为典型ESES组、非典型ESES组和非ESES组。对临床和脑电图特征进行了回顾性分析。采用逻辑回归法确定ESES的风险因素。结果共有 95 名 SeLECTS 患者入选。7名患者(7.4%)出现典型ESES,30名患者(31.6%)出现非典型ESES,25名患者(26.3%)在首次就诊时出现ESES,12名患者(12.6%)在治疗和随访期间出现ESES。多变量逻辑回归分析显示,SeLECTS合并ESES的风险因素是罗兰尼克双峰或多峰(OR = 8.626,95% CI:2.644-28.147,P P 结论。超过三分之一的 SeLECTS 患者合并有 ESES。非典型和典型 ESES 评分都会影响认知功能。在脑电图上,发作间期罗兰双/多棘波和慢波异常可能预示着 SeLECTS 合并 ESES。
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来源期刊
Clinical EEG and Neuroscience
Clinical EEG and Neuroscience 医学-临床神经学
CiteScore
5.20
自引率
5.00%
发文量
66
审稿时长
>12 weeks
期刊介绍: Clinical EEG and Neuroscience conveys clinically relevant research and development in electroencephalography and neuroscience. Original articles on any aspect of clinical neurophysiology or related work in allied fields are invited for publication.
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