Why now and not later? An exploration into the neurocognitive correlates of delay discounting in bipolar disorder

Alexandra K. Gold, Michael W. Otto
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Abstract

Increased delay discounting is evident in bipolar disorder, though there is minimal research on the factors that impact delay discounting in this population. We evaluated neurocognitive correlates of delay discounting among relatively euthymic participants with bipolar disorder (N ​= ​76) with (n ​= ​31) and without (n ​= ​45) past-year substance use disorders. There were no significant differences in the mean delay discounting value between the bipolar disorder group and the comorbid bipolar disorder and past-year substance use disorders group (p ​= ​.082, Cohen's d ​= ​0.41). Using multiple regression, we evaluated the most important predictors of the delay discounting value. Impairments in executive functioning (per number of categories completed on the Wisconsin Card Sorting Test) and visuospatial construction (per the Rey-Osterrieth Complex Figure Test Copy Raw Score), as well as decreased years of education (all ps ​< ​.05), offered the best neurocognitive characterization of increased delay discounting in this sample.

为什么是现在而不是以后?双相情感障碍延迟折扣的神经认知相关因素探讨
延迟折扣的增加在双相情感障碍中是明显的,尽管对该人群中影响延迟折扣的因素的研究很少。我们评估了双相情感障碍(N​=​76)与(n​=​31)和不带(n​=​45)过去一年的物质使用障碍。双相情感障碍组与合并双相情感疾病和过去一年药物使用障碍组之间的平均延迟贴现值没有显著差异(p​=​.082,科恩的d​=​0.41)。使用多元回归,我们评估了延迟贴现值的最重要预测因素。执行功能受损(根据威斯康星卡片分类测试中完成的类别数量)和视觉空间构建受损(根据Rey-Osterrieth复杂图形测试副本原始分数),以及受教育年限减少(所有ps​<;​.05),提供了该样本中延迟折扣增加的最佳神经认知特征。
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来源期刊
Psychiatry research communications
Psychiatry research communications Psychiatry and Mental Health
CiteScore
1.40
自引率
0.00%
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0
审稿时长
77 days
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