Asymptomatic surveillance testing for COVID-19 in health care professional students: lessons learned from a low prevalence setting.

Alyssa G Burrows, Sophia Linton, Jenny Thiele, Prameet M Sheth, Gerald A Evans, Stephen Archer, Katharine M Doliszny, Marcia Finlayson, Leslie Flynn, Yun Huang, Azim Kasmani, T Hugh Guan, Allison Maier, Adrienne Hansen-Taugher, Kieran Moore, Anthony Sanfilippo, Erna Snelgrove-Clarke, Dean A Tripp, David M C Walker, Stephen Vanner, Anne K Ellis
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Abstract

The novel coronavirus disease of 2019 (COVID-19) pandemic has severely impacted the training of health care professional students because of concerns of potential asymptomatic transmission to colleagues and vulnerable patients. From May 27th, 2020, to June 23rd 2021; at a time when B.1.1.7 (alpha) and B.1.617.2 (delta) were the dominant circulating variants, PCR testing was conducted on 1,237 nasopharyngeal swabs collected from 454 asymptomatic health care professional students as they returned to their studies from across Canada to Kingston, ON, a low prevalence area during that period for COVID-19. Despite 46.7% of COVID-19 infections occurring in the 18-29 age group in Kingston, severe-acute-respiratory coronavirus-2 was not detected in any of the samples suggesting that negligible asymptomatic infection occurred in this group and that PCR testing in this setting may not be warranted as a screening tool.

Abstract Image

Abstract Image

卫生保健专业学生COVID-19无症状监测检测:从低患病率环境中吸取的教训
2019年新型冠状病毒病(COVID-19)大流行严重影响了卫生专业学生的培训,因为人们担心可能会将无症状传播给同事和弱势患者。2020年5月27日至2021年6月23日;在B.1.1.7 (α)和B.1.617.2 (δ)是主要的流行变异的时候,对从454名无症状的卫生保健专业学生收集的1237份鼻咽拭子进行了PCR检测,这些学生从加拿大各地返回安大略省金斯顿(当时是COVID-19的低流行区)学习。尽管46.7%的COVID-19感染发生在金斯敦的18-29岁年龄组,但在任何样本中均未检测到严重急性呼吸道冠状病毒-2,这表明在该组中发生了可忽略不计的无症状感染,并且在这种情况下PCR检测可能不值得作为筛查工具。
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