Repeatability of a fully automated swept-source optical coherence tomography biometer and agreement with a low coherence reflectometry biometer.

IF 5.4 3区材料科学 Q2 CHEMISTRY, PHYSICAL

ACS Applied Energy Materials Pub Date : 2023-06-02 DOI:10.1186/s40662-023-00343-4

Alberto Domínguez-Vicent, Abinaya Priya Venkataraman, Amanda Dalin, Rune Brautaset, Robert Montés-Micó

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Abstract

Background: To evaluate the repeatability of a fully automated swept-source optical coherence tomography (SS-OCT) and its agreement with an optical low coherence reflectometry (OLCR) for several biometric parameters.

Methods: In this study, 74 eyes of 74 patients were measured using the Eyestar 900 SS-OCT and Lenstar LS 900 OLCR. Flat keratometry (K1) and steep keratometry (K2), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), and axial length (AL) were measured three times with each device. The repeatability was analyzed with the intrasubject standard deviation, coefficient of variability (CoV), and coefficient of repeatability (CoR) for each instrument. The agreement between the instruments was evaluated with Bland-Altman analysis.

Results: K1, K2 and CCT CoV values were < 0.2%, < 0.4% and < 0.55%, respectively. Higher CoV values were found for ACD and LT ranging from 0.56% to 1.74%. The lowest CoV values were found for the AL measurements (0.03% and 0.06% for the Eyestar 900 and the Lenstar LS 900, respectively). AL measurements provided the highest repeatability, measured with both CoV and CoR values, and the CCT was the parameter with the lowest repeatability. The CCT and LT measurements were statistically significant between the two biometers (P < 0.001). The interval of the limits of agreement was < 0.6 D for K1 and K2, 15.78 µm for CCT, 0.21 mm for ACD, 0.34 mm for LT, and 0.08 mm for AL.

Conclusions: Both biometers provide repeatable measurements for the different parameters analyzed and can be used interchangeably.

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全自动扫描源光学相干层析生物计的可重复性与低相干反射生物计的一致性。

背景:评估全自动扫源光学相干层析成像(SS-OCT)的重复性及其与光学低相干反射仪(OLCR)在几个生物特征参数上的一致性。方法:采用Eyestar 900 SS-OCT和Lenstar ls900 OLCR对74例患者74只眼进行测量。每台仪器分别测量3次角膜平度(K1)和陡度(K2)、角膜中央厚度(CCT)、前房深度(ACD)、晶状体厚度(LT)和轴向长度(AL)。用每个仪器的受试者内标准差、变异系数(CoV)和可重复性系数(CoR)分析可重复性。用Bland-Altman分析评估仪器之间的一致性。结果:K1、K2和CCT CoV值均为阳性。结论:两种生物测量仪对不同的分析参数具有可重复性，可互换使用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Applied Energy Materials Materials Science-Materials Chemistry

CiteScore

10.30

自引率

6.20%

发文量

1368

期刊介绍： ACS Applied Energy Materials is an interdisciplinary journal publishing original research covering all aspects of materials, engineering, chemistry, physics and biology relevant to energy conversion and storage. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important energy applications.