[Surgery of old people-Thoracic surgery].

Jonas Peter Ehrsam, Clemens Aigner
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Abstract

Background: The incidence of a large number of diseases relevant to thoracic surgery increases with age; however, old age is still frequently considered a contraindication per se for curative interventions and extensive surgical procedures.

Objective: Overview of the current relevant literature, derivation of recommendations for patient selection as well as preoperative, perioperative and postoperative optimization.

Material and methods: Analysis of the current study situation.

Results: Recent data show that for most thoracic diseases, age alone is not a reason to withhold surgical treatment. Much more important for the selection are comorbidities, frailty, malnutrition and cognitive impairment. A lobectomy or segmentectomy for stage I non-small cell lung cancer (NSCLC) in carefully selected octogenarians can provide acceptable to even comparably good short-term and long-term results as in younger patients. Selected > 75-year-old patients with stages II-IIIA NSCLC even benefit from adjuvant chemotherapy. With appropriate selection high-risk interventions, such as pneumonectomy in > 70-year-old patients and pulmonary endarterectomy in > 80-year-old patients can be performed without an increase in mortality rates. Even lung transplantation can lead to good long-term results in carefully selected > 70-year-old patients. Minimally invasive surgical techniques and nonintubated anesthesia contribute to risk reduction in marginal patients.

Discussion: In thoracic surgery the biological age rather than the chronological age is decisive. In view of the increasingly older population, further studies are urgently needed to optimize patient selection, type of intervention, preoperative planning and postoperative treatment as well as the quality of life.

Abstract Image

【老年人胸外科】。
背景:大量与胸外科相关的疾病的发病率随着年龄的增长而增加;然而,老年仍然经常被认为是治疗干预和广泛手术的禁忌症。目的:综述目前的相关文献,推导患者选择的建议以及术前、围手术期和术后的优化。材料与方法:分析研究现状。结果:最近的数据表明,对于大多数胸部疾病,年龄本身并不是拒绝手术治疗的理由。对于选择来说,更重要的是合并症、虚弱、营养不良和认知障碍。在精心选择的八旬老人中,对I期非小细胞肺癌癌症(NSCLC)进行肺叶切除术或节段切除术可以提供可接受的、甚至与年轻患者一样好的短期和长期结果。选定> 75岁的II-IIIA期NSCLC患者甚至受益于辅助化疗。选择适当的高危干预措施,如> 70岁患者和肺动脉内膜切除术 80岁的患者可以在不增加死亡率的情况下进行手术。即使是肺移植也可以在精心选择的> 70岁的患者。微创手术技术和非插管麻醉有助于降低边缘患者的风险。讨论:在胸部手术中,决定因素是生理年龄,而不是实际年龄。鉴于年龄越来越大,迫切需要进一步研究,以优化患者选择、干预类型、术前计划和术后治疗以及生活质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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