Application of Equal Local Levels to Improve Q-Q Plot Testing Bands with R Package qqconf.

IF 5.4 2区 计算机科学 Q1 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS
Eric Weine, Mary Sara McPeek, Mark Abney
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引用次数: 3

Abstract

Quantile-Quantile (Q-Q) plots are often difficult to interpret because it is unclear how large the deviation from the theoretical distribution must be to indicate a lack of fit. Most Q-Q plots could benefit from the addition of meaningful global testing bands, but the use of such bands unfortunately remains rare because of the drawbacks of current approaches and packages. These drawbacks include incorrect global Type I error rate, lack of power to detect deviations in the tails of the distribution, relatively slow computation for large data sets, and limited applicability. To solve these problems, we apply the equal local levels global testing method, which we have implemented in the R Package qqconf, a versatile tool to create Q-Q plots and probability-probability (P-P) plots in a wide variety of settings, with simultaneous testing bands rapidly created using recently-developed algorithms. qqconf can easily be used to add global testing bands to Q-Q plots made by other packages. In addition to being quick to compute, these bands have a variety of desirable properties, including accurate global levels, equal sensitivity to deviations in all parts of the null distribution (including the tails), and applicability to a range of null distributions. We illustrate the use of qqconf in several applications: assessing normality of residuals from regression, assessing accuracy of p values, and use of Q-Q plots in genome-wide association studies.

等局部水平在R包qconf改进Q-Q地块测试波段中的应用。
分位数-分位数(Q-Q)图通常很难解释,因为不清楚与理论分布的偏差有多大才能表明缺乏拟合。大多数Q-Q图都可以从增加有意义的全局测试波段中受益,但不幸的是,由于当前方法和封装的缺点,这种波段的使用仍然很少。这些缺点包括不正确的全局I型错误率,缺乏检测分布尾部偏差的能力,对大型数据集的计算相对较慢,以及有限的适用性。为了解决这些问题,我们应用了我们在R Package qqconf中实现的等局部水平全局测试方法,这是一个多功能工具,可以在各种设置中创建Q-Q图和概率-概率(P-P)图,并使用最新开发的算法快速创建同步测试波段。qqconf可以很容易地将全局测试带添加到其他包制作的Q-Q图中。除了快速计算之外,这些波段具有各种理想的特性,包括准确的全局电平,对零分布的所有部分(包括尾部)的偏差具有相同的灵敏度,以及对零分布范围的适用性。我们举例说明了qqconf在以下几个应用中的使用:评估回归残差的正态性,评估p值的准确性,以及在全基因组关联研究中使用Q-Q图。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Statistical Software
Journal of Statistical Software 工程技术-计算机:跨学科应用
CiteScore
10.70
自引率
1.70%
发文量
40
审稿时长
6-12 weeks
期刊介绍: The Journal of Statistical Software (JSS) publishes open-source software and corresponding reproducible articles discussing all aspects of the design, implementation, documentation, application, evaluation, comparison, maintainance and distribution of software dedicated to improvement of state-of-the-art in statistical computing in all areas of empirical research. Open-source code and articles are jointly reviewed and published in this journal and should be accessible to a broad community of practitioners, teachers, and researchers in the field of statistics.
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