Dopamine Agonist-Induced Cerebrospinal Fluid Rhinorrhoea: A Case Report.

Journal of cancer & allied specialties Pub Date : 2021-01-06 eCollection Date: 2021-01-01 DOI:10.37029/jcas.v7i1.389
Hira Irfan, Ahmed Imran Siddiqi, Umal Azmat, Waqas Shafiq, Irfan Yousaf, Muhammad Atif Naveed
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引用次数: 1

Abstract

Introduction: Prolactinomas are the most common pituitary adenomas. Medical therapy with dopamine agonists (DAs) is the mainstay of treatment and rarely requires surgical manipulation. Patients may rarely present with cerebrospinal fluid (CSF) rhinorrhoea after starting therapy with DA in case of massive or invasive prolactinomas.

Case description: We present a case of a 29-year-old lady with invasive prolactinoma who presented with CSF rhinorrhoea after a month of starting bromocriptine therapy with the development of meningitis and warranting early surgical repair.

Practical implications: Patients with macroprolactinoma should be closely monitored initially after starting on DA to avoid life-threatening complications.

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多巴胺激动剂诱发脑脊液鼻出血一例报告。
引言:泌乳素腺瘤是最常见的垂体腺瘤。多巴胺激动剂(DA)的药物治疗是主要的治疗方法,很少需要手术操作。在大规模或侵袭性泌乳素瘤的情况下,患者在开始DA治疗后可能很少出现脑脊液(CSF)鼻出血。病例描述:我们报告了一例29岁的侵袭性泌乳素瘤患者,她在开始溴隐亭治疗一个月后出现脑脊液鼻出血,并发展为脑膜炎,需要早期手术修复。实际意义:大泌乳素腺瘤患者在开始服用DA后应首先密切监测,以避免危及生命的并发症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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