Adipose-derived Stem Cells: Potentials, Availability and Market Size in Regenerative Medicine.

IF 2.1 4区 医学 Q4 CELL & TISSUE ENGINEERING
Adele Soltani, Maryam Moradi, Aida Rezaei Nejad, Shabnam Moradi, Ehsan Javandoost, Hojjatollah Nazari, Arefeh Jafarian
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引用次数: 2

Abstract

Adipose-derived stem cells (ADSCs) have been described as one of the most potent and accessible human adult stem cells which can be utilized in various therapeutic approaches. Due to the wide variety of cytokines and GFs secreted by them, ADSCs can be used for controlled drug release. These cells can be used for proliferation and differentiation of tissues regardless of survival conditions and immunologic problems. Because of their ability to differentiate into various lineages, ADSCs can be used in musculoskeletal problems, diabetes, heart diseases, obesity, neurologic and nephrogenic diseases, and wound healing, as well as applications in regenerative medicine such as osteogenic, cartilage, tendon, muscle, skin, CNS, cardiac and vascularization, as well as liver and even periodontal regeneration. To maintain the highest viability and efficiency, companies that provide ADSCs should offer the best product quality to gain market share and scientists need to acquire an understanding of sources where they can find the best products available. Therefore, in this article, we have reviewed the available products, companies and the market size currently available for ADSCs. Enormous effort has been made to list the most important trials, products and companies currently existent in the field. To achieve better outcomes in scientific research, there is the need to compare the products available and choose the best option according to desired goals. Thus, this paper provides a valuable reference for those interested in the field of ADSCs and their applications.

脂肪来源的干细胞:再生医学的潜力、可用性和市场规模。
脂肪源性干细胞(ADSCs)被认为是最有效和最容易获得的人类成体干细胞之一,可用于各种治疗方法。由于其分泌的细胞因子和生长因子种类繁多,ADSCs可用于控制药物释放。这些细胞可以用于组织的增殖和分化,而不受生存条件和免疫问题的影响。由于ADSCs能够分化成各种谱系,因此可用于肌肉骨骼问题、糖尿病、心脏病、肥胖、神经和肾源性疾病、伤口愈合,以及在再生医学中的应用,如成骨、软骨、肌腱、肌肉、皮肤、中枢神经系统、心脏和血管化,以及肝脏甚至牙周再生。为了保持最高的生存能力和效率,提供ADSCs的公司应该提供最好的产品质量来获得市场份额,科学家需要了解他们可以找到最好产品的来源。因此,在本文中,我们回顾了可用的产品,公司和市场规模目前可用于adsc。我们付出了巨大的努力,列出了该领域目前存在的最重要的试验、产品和公司。为了在科学研究中取得更好的成果,有必要比较现有的产品,并根据期望的目标选择最佳方案。因此,本文为关注ADSCs及其应用领域的人员提供了有价值的参考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Current stem cell research & therapy
Current stem cell research & therapy CELL & TISSUE ENGINEERING-CELL BIOLOGY
CiteScore
4.20
自引率
3.70%
发文量
197
审稿时长
>12 weeks
期刊介绍: Current Stem Cell Research & Therapy publishes high quality frontier reviews, drug clinical trial studies and guest edited issues on all aspects of basic research on stem cells and their uses in clinical therapy. The journal is essential reading for all researchers and clinicians involved in stem cells research.
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