{"title":"Obituary for Yuri Dubrova (1955-2023).","authors":"Carole Yauk","doi":"10.1093/mutage/gead008","DOIUrl":null,"url":null,"abstract":"Professor Yuri Dubrova’s research transformed our understanding of environmental mediators of heritable genetic effects. His discovery that the tools and loci used in DNA forensic sciences could be repurposed to study induced mutagenesis opened the door to research investigating the relationship between environmental exposures and germ cell mutations in species across kingdoms. His provocative findings that low-dose radiation exposures in humans are associated with increased rates of heritable germ cell mutations set the stage for contentious debates around the world. He has undoubtedly left an indelible mark on the field of mutation research. Dubrova","PeriodicalId":18889,"journal":{"name":"Mutagenesis","volume":"38 2","pages":"81-83"},"PeriodicalIF":2.5000,"publicationDate":"2023-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181793/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Mutagenesis","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/mutage/gead008","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"GENETICS & HEREDITY","Score":null,"Total":0}
引用次数: 0
Abstract
Professor Yuri Dubrova’s research transformed our understanding of environmental mediators of heritable genetic effects. His discovery that the tools and loci used in DNA forensic sciences could be repurposed to study induced mutagenesis opened the door to research investigating the relationship between environmental exposures and germ cell mutations in species across kingdoms. His provocative findings that low-dose radiation exposures in humans are associated with increased rates of heritable germ cell mutations set the stage for contentious debates around the world. He has undoubtedly left an indelible mark on the field of mutation research. Dubrova
期刊介绍:
Mutagenesis is an international multi-disciplinary journal designed to bring together research aimed at the identification, characterization and elucidation of the mechanisms of action of physical, chemical and biological agents capable of producing genetic change in living organisms and the study of the consequences of such changes.