Definition of normal blood pressure at 11 to 14 weeks' gestation according to risk.

IF 0.7 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Archivos de cardiologia de Mexico Pub Date : 2023-01-01 DOI:10.24875/ACM.21000247

Yamile L Valenzuela-Muhech, Alfredo J Cervantes-Ricaud, Erika R Carrasco-Blancas, Marco A Cortes-Martínez, Héctor Oviedo-Cruz

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Abstract

Objective: To define normal blood pressure at first trimester of pregnancy by performance for pre-eclampsia prediction.

Method: A cohort study in singleton pregnancies, according to the competing risks model for pre-eclampsia. Blood pressure was measured according to a standardized method at 11 to 14 weeks' gestation.

Results: Among 797 pregnancies included, there were 40 (5.0%, IC95 3.6; 6.4) deliveries with pre-eclampsia. The systolic, diastolic, and mean arterial blood pressures were respectively of 101(9), 68(8) and 79(8) mmHg in pregnant women who did not develop pre-eclampsia, against 109(10), 75(8) and 86(8) in those who did (p < 0.001, t-test). The areas under the curves were 0.707 (0.637; 0.777), 0.728 (0.661; 0.795), and 0.738 (0.673; 0.803). At a 3% of false positive rate, the cut-off points were 119, 83 and 94 mmHg with predictive values of negative of 95.6%.

Conclusions: It is feasible to define the normal values for blood pressure in pregnancy on biostatistic and clinical basis.

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妊娠11至14周时根据风险定义正常血压。

目的:通过对先兆子痫表现的预测，确定妊娠早期正常血压。方法:根据子痫前期竞争风险模型，对单胎妊娠患者进行队列研究。在妊娠11 ~ 14周按标准化方法测量血压。结果:797例妊娠中，40例(5.0%，IC95 3.6;6.4)先兆子痫分娩。未发生子痫前期的孕妇的收缩压、舒张压和平均动脉血压分别为101(9)、68(8)和79(8)mmHg，而发生子痫前期的孕妇的收缩压、舒张压和平均动脉血压分别为109(10)、75(8)和86(8)(p < 0.001, t检验)。曲线下面积为0.707 (0.637;0.777)， 0.728 (0.661;0.795)， 0.738 (0.673;0.803)。在假阳性率为3%的情况下，分界点分别为119、83和94 mmHg，阴性预测值为95.6%。结论:从生物统计学和临床基础上确定妊娠期血压正常值是可行的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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